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 Phantom


Overall Research Goal

To advance instrumentation technologies, image reconstruction techniques, and image processing and analysis methods that lead to improved quality and quantitative accuracy in radiological images for better clinical diagnosis and other biomedical applications.

Current Imaging Modalities of Focus
 Nuclear medicine including SPECT and PET for clinical and small animal imaging
X-ray CT for clinical and small animal imaging
CT-like soft tissue imaging with flat panel C-arm system
Dual energy x-ray absorptiometry for measuring tissue composition and bone mechanical   properties

Representative Research Projects

Imaging Modalities and applications

SPECT:

Dual isotope SPECT imaging techniques
Quantitative, gated myocardial SPECT
Rotating multi-segment slant-hole (RMSSH) SPECT
Quantitative oncological SPECT
Monte Carlo simulation methods
Multi-pinhole micor-SPECT
Multi-dimensional analytical and statistical image reconstruction methods for SPECT

PET:

Respiratory- and cardiac-gated PET
Performance evaluation of small animal PET scanner
Monte Carlo simulation methods
Multi-dimensional analytical and statistical image reconstruction methods for PET

CT:

Micro-CT systems
Statistical reconstruction methods for transmission tomography
Cardiac CT
Time resolved volumetric imaging for x-ray CT
Analytical reconstruction methods for x-ray CT
Dual-kVp CT
Radiation dose in multidetector-row CT (MDCT)

SPECT/CT:

Molecular imaging using Micro-SPECT/CT techqniues

X-ray:

Bone mechanical properties using X-ray imaging technique
Dual energy absorptiometry for measuring tissue composition

Interventional Radiology (IVR):

Evaluation of 3D and soft tissue imaging
Radiation dose optimization

Tool development

Phantoms:

4D NCAT (Heart, lung, brain, liver, etc.)
MOBY
4D MCAT

Image quality evaluations:

Image quality indices
Task-based image evaluation methods
Channelized Hoteling Observer (CHO) study
Standard ROC, LROC, FROC and Three-class ROC methodologies
Human observer study

Simulators:

Analytical simulators for SPECT, PET and x-ray CT
Monte Carlo simulations for SPECT, PET, and x-ray CT
Department of Radiology Johns Hopkins MedicineJohns Hopkins University
©Copyright 2003 | All Rights Reserved; last modified 07-July-2003
Division of Medical Imaging Physics, Johns Hopkins Medical Instituions, 601 North Caroline Street, JHOC Room 4263, Baltimore, MD 21287-0859 USA