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Evaluation of 3D and soft tissue imaging: Transcatheter arterial chemo embolization (TACE)
Background and Research Goal

C-arm systems used in the interventional radiology (IVR) have the capability of volumetric (3D) imaging and the soft tissue imaging. Working closely with interventional tumor oncologists, the goal of this study is (1) to evaluate the utility of soft tissue imaging in abdominal IVR procedures, and (2) to develop new clinical applications using the 3D and/or soft tissue images.
Methods

The detail will be posted soon.

Shown below is our initial experience. The early arterial phase (20 sec after the injection) of the contrast enhanced MRI (left), “post-treatment” CT-like soft tissue imaging during the TACE procedure (middle) and the plain CT scans taken one day after the TACE procedure (right) show beautiful correlation of the tumor location and the treatment results.

 
 

Representive Result
Up to now, we verified that the iodine concentration can be quantified within 10% accuracy (Pub. 1). We are interested in assessing the correlation in each pixel between Lipiodol distribution and tumor response.
Research Team
Jean H. Francois Geschwind, M.D. (P.I.)
Katsuyuki Taguchi, Ph.D.
Mengxi Zhang, B.S.

 
Supporting Grant
This work is funded by Philips Medical Systems (Best, The Netherlands).

 
Publication

1. Funama Y, Graff DS, Geschwind JFH, Fishman EK, and Taguchi K, “The Quantitative Measurement of Iodine Concentration with Abdominal C-arm CT: Phantom Study,” to be presented at World Conference on Interventional Oncology, May 14-17, 2007 (Washington DC, USA).

References

To be posted soon.

 
Department of Radiology Johns Hopkins MedicineJohns Hopkins University
©Copyright 2003 | All Rights Reserved; last modified 07-July-2003
Division of Medical Imaging Physics, Johns Hopkins Medical Institutions, 601 North Caroline Street, JHOC Room 4263, Baltimore, MD 21287-0859 USA