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 Phantom

  Eric C. Frey, Ph.D

    1.        E.C. Frey and B.M.W. Tsui, "Parameterization of the Scatter Response Function in SPECT Imaging Using Monte-Carlo Simulation," IEEE Trans Nucl Sci, 37(3): 1308-1315, 1990.

     

    2.        E.C. Frey and B.M.W. Tsui, "Spatial Properties of the Scatter Response Function in SPECT," IEEE Trans Nucl Sci, 38(2): 789-794, 1991.

     

    3.        B.M.W. Tsui, X.D. Zhao, E.C. Frey, and G.T. Gullberg, "Comparison between ML-EM and WLS-CG Algorithms for SPECT Image-Reconstruction," IEEE Trans Nucl Sci, 38(6): 1766-1772, 1991.

     

    4.        E.C. Frey, B.M.W. Tsui, and J.R. Perry, "Simultaneous Acquisition of Emission and Transmission Data for Improved Tl-201 Cardiac SPECT Imaging Using a Tc-99m Transmission Source," J Nucl Med, 33(12): 2238-2245, 1992.

     

    5.        E.C. Frey, Z.W. Ju†, and B.M.W. Tsui, "A Fast Projector-Backprojector Pair Modeling the Asymmetric, Spatially Varying Scatter Response Function for Scatter Compensation in SPECT Imaging," IEEE Trans Nucl Sci, 40(4): 1192-1197, 1993.

     

    6.        E.C. Frey and B.M.W. Tsui, "A Practical Method for Incorporating Scatter in a Projector-Backprojector for Accurate Scatter Compensation in SPECT," IEEE Trans Nucl Sci, 40(4): 1107-1116, 1993.

     

    7.        B.M.W. Tsui, X.D. Zhao, Z.J. Cao, and E.C. Frey, "Reconstruction Methods for Quantitative Brain SPECT," IEEE Trans Nucl Sci, 40(2): 214-220, 1993.

     

    8.        F.J. Beekman, E.C. Frey, C. Kamphuis, B.M.W. Tsui, and M.A. Viergever, "A New Phantom for Fast Determination of the Scatter Response of a Gamma-Camera," IEEE Trans Nucl Sci, 41(4): 1481-1488, 1994.

     

    9.        Z.J. Cao, E.C. Frey, and B.M.W. Tsui, "A Scatter Model for Parallel and Converging Beam SPECT Based on the Klein-Nishina Formula," IEEE Trans Nucl Sci, 41(4): 1594-1600, 1994.

     

    10.     E.C. Frey and B.M.W. Tsui, "Modeling the Scatter Response Function in Inhomogeneous Scattering Media for SPECT," IEEE Trans Nucl Sci, 41(4): 1585-1593, 1994.

     

    11.     B.M.W. Tsui, E.C. Frey, X. Zhao, D.S. Lalush, R.E. Johnston, and W.H. McCartney, "The Importance and Implementation of Accurate 3d Compensation Methods for Quantitative SPECT," Phys Med Biol, 39(3): 509-530, 1994.

     

    12.     B.M.W. Tsui, X.D. Zhao, E.C. Frey, and W.H. McCartney, "Quantitative Single-Photon Emission Computed-Tomography - Basics and Clinical Considerations," Semin Nucl Med, 24(1): 38-65, 1994.

     

    13.     B.M.W. Tsui, X.D. Zhao, G.K. Gregoriou, D.S. Lalush, E.C. Frey, R.E. Johnston, and W.H. McCartney, "Quantitative Cardiac SPECT Reconstruction with Reduced Image Degradation Due to Patient Anatomy," IEEE Trans Nucl Sci, 41(6): 2838-2844, 1994.

     

     

    14.     E.C. Frey and B.M.W. Tsui, "A Comparison of Gd-153 and Co-57 as Transmission Sources for Simultaneous Tct and Tl-201 SPECT," IEEE Trans Nucl Sci, 42(4): 1201-1206, 1995.

     

    15.     Z.W. Ju†, E.C. Frey, and B.M.W. Tsui, "Distributed 3-D Iterative Reconstruction for Quantitative SPECT," IEEE Trans Nucl Sci, 42(4): 1301-1309, 1995.

     

    16.     J. Li, B.M.W. Tsui, A. Welch, E.C. Frey, and G.T. Gullberg, "Energy Window Optimization in Simultaneous Tc-99m Tct and Thallium-2o1 SPECT Data-Acquisition," IEEE Trans Nucl Sci, 42(4): 1207-1213, 1995.

     

    17.     D.J. Kadrmas†, E.C. Frey, and B.M.W. Tsui, "An SVD investigation of modeling scatter in multiple energy windows for improved SPECT images," IEEE Trans Nucl Sci, 43(4): 2275-2284, 1996.

     

    18.     F.J. Beekman, C. Kamphuis, and E.C. Frey, "Scatter compensation methods in 3D iterative SPECT reconstruction: A simulation study," Phys Med Biol, 42(8): 1619-1632, 1997.

     

    19.     D.J. Kadrmas†, E.C. Frey, and B.M.W. Tsui, "Analysis of the reconstructibility and noise properties of scattered photons in Tc-99m SPECT," Phys Med Biol, 42(12): 2493-2516, 1997.

     

    20.     E.C. Frey, B.M.W. Tsui, and G.T. Gullberg, "Improved estimation of the detector response function for converging beam collimators," Phys Med Biol, 43(4): 941-950, 1998.

     

    21.     D.J. Kadrmas†, E.C. Frey, S.S. Karimi†, and B.M.W. Tsui, "Fast implementations of reconstruction-based scatter compensation in fully 3D SPECT image reconstruction," Phys Med Biol, 43(4): 857-873, 1998.

     

    22.     D.J. Kadrmas†, E.C. Frey, and B.M.W. Tsui, "Application of reconstruction-based scatter compensation to thallium-201 SPECT: Implementations for reduced reconstructed image noise," IEEE Trans Med Imaging, 17(3): 325-333, 1998.

     

    23.     B.M.W. Tsui, E.C. Frey, K.J. LaCroix, D.S. Lalush, W.H. McCartney, M.A. King, and G.T. Gullberg, "Quantitative myocardial perfusion SPECT," J Nucl Cardiol, 5(5): 507-522, 1998.

     

    24.     B.M.W. Tsui, D.E. Wessell, X.D. Zhao, W.T. Wang, D.P. Lewis, and E.C. Frey, "Imaging characteristics of scintimammography using parallel-hole and pinhole collimators," IEEE Trans Nucl Sci, 45(4): 2155-2161, 1998.

     

    25.     S.D. Wollenweber, B.M.W. Tsui, D.S. Lalush, E.C. Frey, and G.T. Gullberg, "Evaluation of myocardial defect detection between parallel-hole and fan-beam SPECT using the Hotelling trace," IEEE Trans Nucl Sci, 45(4): 2205-2210, 1998.

     

    26.     D.J. Kadrmas†, E.C. Frey, and B.M.W. Tsui, "Simultaneous technetium-99m/thallium-201 SPECT imaging with model-based compensation for cross-contaminating effects," Phys Med Biol, 44(7): 1843-1860, 1999.

     

    27.     S.D. Wollenweber, B.M.W. Tsui, D.S. Lalush, E.C. Frey, K.J. LaCroix, and G.T. Gullberg, "Comparison of hotelling observer models and human observers in defect detection from myocardial SPECT imaging," IEEE Trans Nucl Sci, 46(6): 2098-2103, 1999.

     

    28.     K.J. LaCroix, B.M.W. Tsui, E.C. Frey, and R.J. Jaszczak, "Receiver operating characteristic evaluation of iterative reconstruction with attenuation correction in Tc-99m-sestamibi myocardial SPECT images," J Nucl Med, 41(3): 502-513, 2000.

     

    29.     D.S. Lalush, E.C. Frey, and B.M.W. Tsui, "Fast maximum entropy approximation in SPECT using the RBI-MAP algorithm," IEEE Trans Med Imaging, 19(4): 286-294, 2000.

     

    30.     L.R. MacDonald, B.E. Patt, J.S. Iwanczyk, B.M.W. Tsui, Y.C. Wang, E.C. Frey, D.E. Wessell, P.D. Acton, and H.F. Kung, "Pinhole SPECT of mice using the LumaGEM gamma camera," IEEE Trans Nucl Sci, 48(3): 830-836, 2001.

     

    31.     H.W.A.M. de Jong, W.T. Wang, E.C. Frey, M.A. Viergever, and F.J. Beekman, "Efficient simulation of SPECT down-scatter including photon interactions with crystal and lead," Med Phys, 29(4): 550-560, 2002.

     

    32.     Y. Du†, E.C. Frey, W.T. Wang†, C. Tocharoenchai, W.H. Baird, and B.M.W. Tsui, "Combination of MCNP and SimSET for Monte Carlo simulation of SPECT with medium- and high-energy photons," IEEE Trans Nucl Sci, 49(3): 668-674, 2002.

     

    33.     S. Sankaran†, E.C. Frey, K.L. Gilland, and B.M.W. Tsui, "Optimum compensation method and filter cutoff frequency in myocardial SPECT: A human observer study," J Nucl Med, 43(3): 432-438, 2002. This paper received an award from the Society of Nuclear Medicine for best student paper of 2002.

     

    34.     W.T. Wang†, E.C. Frey, B.M.W. Tsui, C. Tocharoenchai, and W.H. Baird, "Parameterization of Pb X-ray contamination in simultaneous Tl-201 and Tc-99m dual-isotope imaging," IEEE Trans Nucl Sci, 49(3): 680-692, 2002.

     

    35.     M. Ljungberg, K. Sjogreen, X.W. Liu, E. Frey, Y. Dewaraja, and S.E. Strand, "A 3-dimensional absorbed dose calculation method based on quantitative SPECT for radionuclide therapy: Evaluation for I-131 using Monte Carlo simulation," J Nucl Med, 43(8): 1101-1109, 2002.

     

    36.     E.C. Frey., K.L. Gilland, and B.M.W. Tsui, “Application of task-based measures of image quality to optimization and evaluation of three-dimensional reconstruction-based compensation methods in myocardial perfusion SPECT,” IEEE Transactions on Medical Imaging, 2002. 21(9): p. 1040-1050.

     

    37.     Y.S. Gur, T.H. Farncombe, P.H. Pretorius, H.C. Gifford, M.V. Narayanan, E.C. Frey, D. Gagnon, and M.A. King, “Comparison of scatter compensation strategies for myocardial perfusion imaging using Tc-99m labeled sestamibi,” IEEE Transactions on Nuclear Science, 2002. 49(5): p. 2309-2314.

     

    38.     M.K. O'Connor, B. Kemp, F. Anstett, P. Christian, E.P. Ficaro, E. Frey, M. Jacobs, J.N. Kritzman, R.A. Pooley, and M. Wilk, "A multicenter evaluation of commercial attenuation compensation techniques in cardiac SPECT using phantom models," J Nucl Cardiol, 9(4): 361-376, 2002.

     

    39.     T.H. Farncombe, H.C. Gifford, M.V. Narayanan, P.H. Pretorius, E.C. Frey, and M.A. King, “Assessment of scatter compensation strategies for Ga-67 SPECT using numerical observers and human LROC studies,” Journal of Nuclear Medicine, 2004. 45(5): p. 802-812.

     

    40.     M. Ljungberg, E.C. Frey, K. Sjogreen, X.W. Liu, Y. Dewaraja, and S.E. Strand, “3D absorbed dose calculations based on SPECT: Evaluation for 111-In/90-Y therapy using Monte Carlo simulations,” Cancer Biotherapy and Radiopharmaceuticals, 2003. 18(1): p. 99-107.

     

    41.     M.V. Narayanan, P.H. Pretorius, S.T. Dahlberg, J.A. Leppo, N. Botkin, J. Krasnow, W. Berndt, E.C. Frey, and M.A. King, “Evaluation of scatter compensation strategies and their impact on human detection performance Tc-99m myocardial perfusion imaging,” IEEE Transactions on Nuclear Science, 2003. 50(5): p. 1522-1527.

     

    42.     Y. Du†, E.C. Frey, W.T. Wang, and B.M.W. Tsui, “Optimization of acquisition energy windows in simultaneous Tc-99m/I-123 brain SPECT,” IEEE Transactions on Nuclear Science, 2003. 50(5): p. 1556-1561.

     

    43.     X Song†, E.C. Frey, W.T. Wang, Y. Du†, and B.M.W. Tsui, “Validation and evaluation of model-based crosstalk compensation method in simultaneous Tc-99m stress and Tl-201 rest myocardial perfusion SPECT,” IEEE Transactions on Nuclear Science, 2004. 51(1): p. 72-79.

     

    44.     X. He†, E.C. Frey, J.M. Links, K.L. Gilland, W.P. Segars, and B.M.W. Tsui, “A mathematical observer study for the evaluation and optimization of compensation methods for myocardial SPECT using a phantom population that realistically models patient variability,” IEEE Transactions on Nuclear Science, 2004. 51(1): p. 218-224.

     

    45.     Y. Qi, B.M.W. Tsui, K.L. Gilland, E.C. Frey, and G.T. Gullberg, “Evaluation of Parallel and Fan-Beam Data Acquisition Geometries and Strategies for Myocardial SPECT Imaging,” Nuclear Science, IEEE Transactions on, 2004. 51(3): p. 667-672.

     

    46.     W.P. Segars, B.M.W. Tsui BM, E.C. Frey, Johnson GA, Berr SS , “Development of a 4-D digital mouse phantom for molecular imaging research,” Mol Imaging Biol. 2004 May-Jun;6(3):149-59.

     

    47.     C. Tocharoenchai, Benjamin BMW, Frey EC, Wang WT, “Effect of Attenuation Correction on Lesion Detection using a Hybrid PET System”, Journal of the Medical Association of Thailand, 2005, 88(1): pp96-102.

     

    48.     X. Song†, W.P. Segars, Y. Du†, B.M.W. Tsui, E.C. Frey, “Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function,” Phys Med Biol 2005. Apr 21;50(8):1791-804.

     

    49.     Y. Du†, B.M.W. Tsui and E.C. Frey, “Partial volume effect compensation for quantitative brain SPECT imaging,” IEEE Trans Med Imag, 2005, 24 (8) 969-976.

     

    50.     B. He†, Y. Du†, X. Song†, W.P. Segars and E.C. Frey, “A Monte Carlo and physical phantom evaluation of quantitative In-111 SPECT,” Phys Med Biol, 2005, 50(2005) 4169-4185.

     

    51.     W.T. Wang†, E.C. Frey, B.M.W. Tsui, D.S. Lalush, and C. Tocharoenchai, “Optimization of acquisition parameters for simultaneous 201Tl and 99mTc dual-isotope myocardial imaging", IEEE Trans Nucl Sci, 2005, Oct, 52(5) 1277-1235.

     

    52.     X. He†, J.M. Links, X. Song†, B.M.W. Tsui, and E.C. Frey, “Comparison of penetration and scatter effects on defect contrast for GE and Siemens LEHR collimators in myocardial perfusion SPECT – a simulation study,” IEEE Trans Nucl  Sci, 2005, Oct, 52(5) 1359-1364.

     

    53.     Y. Du†, B.M.W. Tsui, E.C. Frey, “Model-based compensation for quantitative 123I brain SPECT imaging,” Phys Med Biol, 2006, Vol. 51, pp:1269-1282.

     

    54.     X. He†, C.E. Metz, B.M.W. Tsui, J.M. Links, E.C. Frey, “Three-class ROC analysis —  a decision theoretic approach,” IEEE Trans Med Imag, 2005, May, 25(5), 2006.

     

    55.     X. He†, J.M. Links, K.L. Gilland, B.M.W. Tsui, E.C. Frey, “Comparison of 180-degree and 360-degree acquisition for myocardial perfusion SPECT with compensation for attenuation, detector response, and scatter: Monte Carlo and mathematical observer results,” J Nucl Cardiol, 2006, June, 13(3), 345-353.

     

    56.     X. He†, E.C Frey, “Three-class ROC analysis — the equal error utility assumption and the optimality of three-class ROC surface using the ideal observer,” in press, IEEE Trans Med Imag.

     

    57.     He B† and Frey EC, “Comparison of Conventional, Model-Based Quantitative Planar, and Quantitative SPECT Image Processing Methods for Organ Activity Estimation Using In-111 Agents,” Physics in Medicine and Biology, Vol.51, pp.3967-3981.

     

    58.     He X† and Frey EC, “Three-Class Hotelling Observer,” accepted for publication in IEEE Trans Med Imag, June 2006.

 
Department of Radiology Johns Hopkins MedicineJohns Hopkins University
©Copyright 2003 | All Rights Reserved; last modified 07-July-2003
Division of Medical Imaging Physics, Johns Hopkins Medical Instituions, 601 North Caroline Street, JHOC Room 4263, Baltimore, MD 21287-0859 USA