Thomas J Beck, Ph.D

Peer Reviewed Original Research Articles:

1.    Beck TJ, Ruff CB, Warden KE, Scott WW, Jr., Rao GU 1990 Predicting femoral neck strength from bone mineral data. A structural approach. Invest Radiol 25(1):6-18.

2.     Beck TJ, Ruff CB, Bissessur K 1993 Age-related changes in female femoral neck geometry: implications for bone strength. Calcif Tissue Int 53 Suppl 1:S41-6.

3.    Beck TJ, Ruff CB, Scott WW, Jr., Plato CC, Tobin JD, Quan CA 1992 Sex differences in geometry of the femoral neck with aging: a structural analysis of bone mineral data. Calcif Tissue Int 50(1):24-9.

4.     Beck T, Ruff C, Mourtada F, Shaffer R, Maxwell-Williams K, Kao G, Sartoris D, Brodine S 1996 DXA Derived Structural Geometry for Stress Fracture Prediction in Male US Marine Corps Recruits. J Bone Mineral Res 11:645-653.

5.     Mourtada F, Beck T, Hauser D, Ruff C, Bao G 1996 A curved beam model of the proximal femur for estimating stress using DXA derived structural geometry. J. Orthop Res 14:483-492.

6.     Mourtada FA, Beck TJ, Links J (1997): “Theoretical Analysis of Error Propagation in Triple Energy Absorptiometry: Application to Measurement of Lead in Bone In Vivo”, Medical Physics, 24:925-927

7.     Bradney M, Pearce G, Naughton G, Sullivan C, Bass S, Beck T, Carlson J, Seeman E 1998 Moderate exercise during growth in prepubertal boys: changes in bone mass, size, volumetric density, and bone strength: a controlled prospective study. J Bone Miner Res. 13(12):1814-21.

8.     Rosenthal LS, Beck TJ, Williams J, Mahesh M, Herman MG, Dinerman JL, Calkins H, Lawrence JH 1997 Acute radiation dermatitis following radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia, Pacing Clin Electrophysiol. 20(7)1834-9.

9.     Rosenthal L.S., Mahadevappa Mahesh M., Beck TJ, Klein L.S., Prystowsky E., Saul J.P., Huang S., Gillette P., Carlson M., Yong P., Lawrence J., Calkins H. (1999):Predictors of Fluoroscopy Time and Estimated Radiation Exposure During Radiofrequency Catheter Ablation Procedures Am J Cardiology, 82:451-458.

10.   Nelson DA, Barondess DA, Hendrix SL, Beck TJ 2000 Cross-sectional geometry, bone strength, and bone mass in the proximal femur in black and white postmenopausal women. J Bone Miner Res 15(10):1992-7.

11.   Beck TJ, Looker AC, Ruff CB, Sievanen H, Wahner HW 2000 Structural trends in the aging femoral neck and proximal shaft: analysis of the Third National Health and Nutrition Examination Survey dual-energy X-ray absorptiometry data. J Bone Miner Res 15(12):2297-304.

12.   Beck TJ, Ruff CB, Shaffer RA, Betsinger K, Trone DW, Brodine SK 2000 Stress fracture in military recruits: gender differences in muscle and bone susceptibility factors. Bone 27(3):437-44.

13.   Crabtree N, Loveridge N, Parker M, Rushton N, Power J, Bell KL, Beck TJ, Reeve J 2001 Intracapsular hip fracture and the region-specific loss of cortical bone: analysis by peripheral quantitative computed tomography. J Bone Miner Res 16(7):1318-28.

14.   Beck TJ, Oreskovic TL, Stone KL, Ruff CB, Ensrud K, Nevitt MC, Genant HK, Cummings SR 2001 Structural adaptation to changing skeletal load in the progression toward hip fragility: the study of osteoporotic fractures. J Bone Miner Res 16(6):1108-19.

15.   Beck TJ, Stone KL, Oreskovic TL, Hochberg MC, Nevitt MC, Genant HK, Cummings SR 2001 Effects of current and discontinued estrogen replacement therapy on hip structural geometry: the study of osteoporotic fractures. J Bone Miner Res 16(11):2103-10.

16.   Charles HJ, Beck T, Feldmesser H, Magee T, Spisz T, Pisacane V 2001 Precision bone and muscle loss measurements by advanced, multiple projection DEXA (AMPDXA) techniques for spaceflight applications. Acta Astronaut. 2001 Aug-Nov; 49:447-50.

17.   Looker AC, Beck TJ, Orwoll ES 2001 Does body size account for gender differences in femur bone density and geometry? J Bone Miner Res 16(7):1291-9.

18.   Petit MA, McKay HA, MacKelvie KJ, Heinonen A, Khan KM, Beck TJ 2002 A randomized school-based jumping intervention confers site and maturity-specific benefits on bone structural properties in girls: a hip structural analysis study. J Bone Miner Res 17(3):363-72.

19.   Lloyd T, Beck TJ, Lin HM, Tulchinsky M, Eggli DF, Oreskovic TL, Cavanagh PR, Seeman E 2002 Modifiable determinants of bone status in young women. Bone 30(2):416-21.

20.   Kaptoge S, Dalzell N, Jakes RW, Wareham N, Day NE, Khaw KT, Beck TJ, Loveridge N, Reeve J 2003 Hip section modulus, a measure of bending resistance, is more strongly related to reported physical activity than BMD. Osteoporos Int 14(11):941-9.

21.   Kaptoge S, Dalzell N, Loveridge N, Beck TJ, Khaw KT, Reeve J 2003 Effects of gender, anthropometric variables, and aging on the evolution of hip strength in men and women aged over 65. Bone 32(5):561-70.

22.   Faulkner RA, Forwood MR, Beck TJ, Mafukidze JC, Russell K, Wallace W 2003 Strength indices of the proximal femur and shaft in prepubertal female gymnasts. Med Sci Sports Exerc 35(3):513-8.

23.   Lloyd T, Petit M, Lin H, Beck T 2004 Lifestyle factors and the development of bone mass and bone strength in young women. J Pediatr 144:776-82.

24.   Petit M, Beck T, Lin H, Bentley C, Legro R, Lloyd T 2004 Femoral bone structural geometry adapts to mechanical loading and is influenced by sex steroids: The Penn State Young Women's Health Study. Bone 35:750-9.

25.   Forwood M, Bailey D, Beck T, Mirwald R, Baxter-Jones A, Uusi-Rasi K 2004 Sexual dimorphism of the femoral neck during the adolescent growth spurt: a structural analysis. Bone 35(4):973-81.

26.   Duan Y, Beck TJ, Wang XF, Seeman E 2003 Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J Bone Miner Res 18(10):1766-74.

27.   Uusi-Rasi K, Beck T, Sievanen H, Heinonen A, Vuori I 2003 Associations of hormone replacement therapy with bone structure and physical performance among postmenopausal women. Bone 32(6):704-10.

28.   MacKelvie K, Petit M, Khan K, Beck T, McKay H 2004 Bone mass and structure are enhanced following a 2-year randomized controlled trial of exercise in prepubertal boys. Bone. 2004 34:755-64.

29.   Szulc P, Uusi-Rasi K, Claustrat B, Marchand F, Beck T, Delmas P 2004 Role of sex steroids in the regulation of bone morphology in men. The MINOS study. Osteoporos Int 15(11):909-17.

30.   Nelson D, Pettifor J, Barondess D, Cody D, Uusi-Rasi K, Beck T 2004 Comparison of cross-sectional geometry of the proximal femur in white and black women from Detroit and Johannesburg. J Bone Miner Res. 2004 19:560-5.

31.   Filardi S, Zebaze R, Duan Y, Edmonds J, Beck T, Seeman E 2004 Femoral neck fragility in women has its structural and biomechanical basis established by periosteal modeling during growth and endocortical remodeling during aging. Osteoporos Int 15:103-7.

32.   Rivadeneira F, Houwing-Duistermaat J, Beck T, Janssen J, Hofman A, Pols H, Van Duijn C, Uitterlinden A 2004 The Influence of an Insulin-Like Growth Factor I Gene Promoter Polymorphism on Hip Bone Geometry and the Risk of Nonvertebral Fracture in the Elderly: The Rotterdam Study. J Bone Miner Res. 19:1280-1290.

33.   Janz KF, Burns TL, Levy SM, Torner JC, Willing MC, Beck TJ, Gilmore JM, Marshall TA 2004 Everyday activity predicts bone geometry in children: the Iowa bone development study. Med Sci Sports Exerc 36(7):1124-31.

34.   Looker A, Beck T 2004 Maternal History of Osteoporosis and Femur Geometry. Calcif Tissue Int 75(4):277-85.

35.   McKay H, MacLean L, Petit M, MacKelvie-O'Brien K, Janssen P, Beck T, Khan K 2005 "Bounce at the Bell": a novel program of short bouts of exercise improves proximal femur bone mass in early pubertal children. Br J Sports Med. 39(8):521-6.

36.   Szulc P, Beck T, Marchand F, Delmas P 2005 Low Skeletal Muscle Mass Is Associated With Poor Structural Parameters of Bone and Impaired Balance in Elderly Men-The MINOS Study. J Bone Miner Res. 20(5):721-9.

37.   Moffett S, Zmuda J, Oakley J, Beck  T, Cauley J, Stone K, Lui L, Ensrud K, Hillier T, Hochberg M, Morin P, Peltz G, Greene D, Cummings S 2005 Tumor Necrosis Factor Alpha Polymorphism, Bone Strength Phenotypes, and the Risk of Fracture in Older Women. J Clin Endocrinol Metab 90((6) ):3491-7.

38.   Melton L, Beck T, Amin S, Khosla S, Achenbach S, Oberg A, Riggs B 2005 Contributions of bone density and structure to fracture risk assessment in men and women. Osteoporos Int. 16(5):460-7.

39.   Uusi-Rasi K, Semanick L, Zanchetta J, Bogado C, Eriksen E, Sato M, Beck T 2005 Effects of Teriparatide [rhPTH (1-34)] Treatment on Structural Geometry of the Proximal Femur in Elderly Osteoporotic Women. Bone 36:948-58.

40.   Khoo B, Beck T, Qiao Q, Parakh Q, Semanick L, Prince R, Singer K, Price R 2005 In vivo short-term reproducibility of hip structure analysis variables in comparison with bone mineral density using paired dual-energy x-ray absorptiometry scans from multi-centre clinical trials. Bone 37:112-21.

41.   Semanick L, Beck T, Cauley J, Wheeler V, Patrick A, Bunker C, Zmuda J 2005 Association of Body Composition and Physical Activity with Proximal Femur Geometry in Middle-Aged and Elderly Afro-Caribbean Men: The Tobago Bone Health Study. Calcif Tissue Int. Sep 15; [Epub ahead of print].

42.   Greenspan S, Beck  T, Resnick N, Bhattacharya R, Parker R 2005 Effect of hormone replacement, alendronate, or combination therapy on hip structural geometry: a 3-year, double-blind, placebo-controlled clinical trial. Bone Miner Res. 20(9):1525-32.

43.   Mayhew P, Thomas C, Clement  J, Loveridge N, Beck T, Bonfield W, Burgoyne C, Reeve J 2005 Relation between age, femoral neck cortical stability, and hip fracture risk. Lancet 366:129-35.

44.   Wang X, Duan Y, Beck T, Seeman E 2005 Varying contributions of growth and ageing to racial and sex differences in femoral neck structure and strength in old age. Bone 36(6):978-86.

45.   Petit M, Beck T, Shults J, Zemel B, Foster B, Leonard M 2005 Proximal femur bone geometry is appropriately adapted to lean mass in overweight children and adolescents. Bone 36(3):568-76.

46.   Cauley J, Lui L, Stone K, Hillier T, Zmuda J, Hochberg M, Beck T, Ensrud K 2005 Loss of Hip Bone Mineral Density is Greater Among Caucasian Women than African American Women. J Am Geriatr Soc. 53(2):183-9.

47.   Uusi-Rasi K, Sievänen H, Heinonen A, Beck T, Vuori I 2005 Determinants of changes in bone structural characteristics and physical performance after menopause: A 9-year follow-up of initially perimenopausal women. Osteoporosis Int 16(6) (6):616-22.

48.   Ashe M, Khan K, Guy P, Lui D, Beck T, McKay H 2006 Improving the Accuracy of pQCT for Evaluating the Aged Human Radius. Osteoporos Int. In Press.

49.   Taylor B, Schreinere P, Zmuda J, Li J, Moffett S, Beck T, Cummings S, Lee J, Walker K, Ensrud K 2006 Association of Endothelial nitric oxide synthase genotypes with bone mineral density, bone loss, hip structure and risk of fracture in older women: The SOF study. Bone 39:174-80.

50.   Forwood M, Baxter-Jones A, Beck T, Mirwald R, Howard A, DA B 2006 Physical activity and strength of the femoral neck during the adolescent growth spurt: A longitudinal analysis. Bone 38:576-83.

51.   Uusi-Rasi K, Sievänen H, Heinonen A, Vuori I, Beck T, Kannus P 2006 Long-term recreational gymnastics provides a clear benefit in age-related functional decline and bone loss: A prospective 6-year study. Osteoporos Int. In Press.

52.   Uusi-Rasi K, Beck T, Semanick L, Dapthary M, Crans G, Desiaha D, Harper K 2006 Structural effects of raloxifene on the proximal femur: results from the multiple outcomes of raloxifene evaluation trial. Osteoporos Int. 17:575-86.

53.   Beck T, Looker A, Mourtada F, Dapthary M, Ruff C 2006 Age trends in femur stresses from a simulated fall on the hip among men and women: Evidence of homeostatic adaptation underlying the decline in hip BMD. J Bone Miner Res. In press.

Review Articles

1.   Beck TJ, Gayler BW: A Review: Image Quality and Radiation Levels in Video fluo­roscopy for Swallowing Studies, Dysphagia 5:118, 1990.

2.   Beck, TJ., Measuring the structural strength of bones with dual -energy x-ray absorptiometry: principles, technical limitations and future possibilities. Osteop Int, 2003. 14 (supp 5): p. S81-88.

3.   Petit, M., T. Beck, and S. Kontulainen, Examining the developing bone: What do we measure and how do we do it? J Musculoskelet Neuronal Interact. , 2005. 5(3): p. 213-24.

Editorials

1.   Beck, TJ: On Predicting Osteoporotic Fracture: Moving Beyond Statistical Inference, 1996 Radiology 199, 612-614.

Book chapters

1.   Beck TJ, Rosenbaum AE, Miller NR: "Orbital Computed Tomography: Technical Aspects" in: Ocular Computed Tomography, Grove, A., Jr. (ed.), Little, Brown, 1982. 

2.   Hrica A, Blome MJ, Beck TJ, Dorst JP: Pediatric  Radiography, in: Ladig, DE. (ed.): Atlas of Roentgenographic Positions and Standard Radiologic Procedures, 5th Ed., C.V. Mosby, 1982. 

3.   Donner MW, Gayler BW, Beck TJ:  "Cineradiography of the Gastrointestinal Tract", in Margulis AR and Burhenne JJ (eds.): Alimentary Tract Radiology, 3rd Ed. C.V. Mosby, 1982.

4.   Rao GU, Scott WW, Beck TJ: "Measurement of Bone Mineral for Early Detection of Osteoporosis", in Computed Tomography of the Musculoskeletal System, Scott WW Jr., Magid D, Fishman EK Eds., Churchill Livingstone,  1987.

5.   Beck TJ, Gayler BW: "Radiation in Video-Recorded Fluoroscopy", in Normal and Abnormal Swallowing: Imaging in Diagnosis and Therapy, B. Jones and MW Donner, Eds., Springer Verlag 1991.

6.   Mahesh M, Gayler BW and Beck TJ: Radiation in Video-Recorded Fluoroscopy, In Normal and Abnormal Swallowing: Imaging in Diagnosis and Therapy , 2^nd Ed. B Jones Editor, Springer Verlag 2000

7.   Beck, TJ: The Prediction of Stress Fracture, in “Musculoskeletal Fatigue and Stress Fractures” DB Burr and C Milgrom editors, pp. 73-83, CRC Press, 2000.