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Benjamin M. W. Tsui, Ph.D. Current Appointments:
Current Business Contact Information: Education and Training:
Professional Experience:
ADMINISTRATIVE APPOINTMENTS Director, Division of Medical Imaging Physics, The Russell H. Morgan Department of Radiology, Johns Hopkins University, July 2002 – present The responsibilies include directing and administrating the Dvision of Medical Medical Imaging Physics including directing the scientific activities and managing research grants and contracts from the NIH, private foundation and industry. The time commitment is 5%. Interim Chair, Department of Biomedical Engineering (BME), UNC-CH, November 2001 – June 2002 The responsiblities are the same as the Chair of the Department of BME during the search for the next Chair of the Department. The time commitment is 10%. Vice Chair, Department of Biomedical Engineering (BME), UNC-CH, January 1999 - October 2001 The responsiblities include consulting and advising the Chair in regard to departmental administration matters and to stand in for the Chair in her absence. The time commitment is 2%. Director of Research and Chair, Research Committee, Department of BME, UNC-CH, 1991 – October 2001 The responsiblities include encouraging and coordinating research activities, acting as the Chair of the Research Committee, and organizing the yearly Department Research Review. The time commitment is 3%. Director, Imaging Track, Department of BME, UNC-CH, 1989-2002 The responsibilies include directing and coordinateing the research and teaching activities in medical and small animal imaging. The time commitment is 5%. Director, Medical Imaging Research Laboratory, Department of BME, UNC-CH, 1988-2002 The responsibilies include directing and managing research grants and contracts from the NIH, private foundation and industry. The time commitment is 10%.
RESEARCH ACTIVITIES
Publications . Chuang LS, and Tsui BMW. Fabrication and Characteristics Study of a Surface Barrier Silicon Solid-State Particle Detector. Am J Phys 40:1679-1683, 1974 2. Metz CE, Tsui BMW, and Beck RN. Theoretical Prediction of the Geometric Transfer Function for Focused Collimators. J Nucl Med 15:1078-1083, 1974 3. Tsui BMW, Beck RN, Metz CE, Atkins FB, and Starr SJ. A Comparison of Optimum Detector Spatial Resolution in Nuclear Imaging Based on Statistical Theory and on Observer performance. Phys Med Biol 23:654-675, 1978 4. Tsui BMW. A Correction to a Comparison of Optimum Detector Spatial Resolution in Nuclear Imaging Based on Statistical Theory and Observer Performance. Phys Med Biol 23:1203, 1978 5. Atkins HL, Robertson JS, Croft BY, Tsui BMW, Suskind H, Ellis KH, Loken MK, and Treves S. Estimates of Radiation Absorbed Doses from Radioxenons in Lung Imaging. J Nucl Med 21:459-465, 1980 6. Tsui BMW, Beck RN, Metz CE, and Doi K. Transfer Function Analysis of the Total Image Forming Process in Nuclear Medicine. J Appl Photo Eng 6:131-140, 1980 7. Tsui BMW, Beck RN, Doi K, and Metz CE. Analysis of Recorded Image Noise in Nuclear Medicine. Phys Med Biol 26:883-902, 1981 8. Tsui BMW, Metz CE, and Beck RN. Optimum Detector Spatial Resolution for Discriminating Between Tumor Uptake Distributions in Scintigraphy. Phys Med Biol 28(7): 775-788, 1983. 9. Tsui BMW, Jaszczak RJ. Interactions of Collimation, Sampling and Filtering on SPECT Spatial Resolution. IEEE on Nucl Sci NS-31 (1): 527-532, 1984 10. Gullberg GT, Crawford CR, and Tsui BMW. Reconstruction Algorithm for Fan Beam with a Displayed Center-of-Rotation. IEEE Trans in Med Imaging MI-5: 23-29, 1986 11. Tsui BMW, Gullberg GT, Edgerton ER, Gilland DR, Perry JR, and McCartney WH. The Design and Clinical Utility of a Fan Beam Collimator for a SPECT System. J Nucl Med 27:810-819, 1986 12. Chang W, Tsui BMW, Tian C, Li S, Williams JJ, Rezai K, Ehrhardt JC, and Kirchner PT. Design and Investigation of a Four-Quadrant Multiple Detector Ring System for Single Photon Emission Computed Tomography (SPECT). SPIE 671:200-205, 1986 13. Saloner D, Moran PR, and Tsui BMW. Velocity Imaging by Rapid Cycle Tagging. Med Phys 14(2):167-171, 1987 14. Moran PR, Saloner D, and Tsui BMW. NMR Velocity-Selective Excitation Composites for Flow and Motion Imaging and Suppression of Static Tissue Signals. IEEE Trans on Med Imag Vol. MI-6(2):141-147, 1987 15. Gullberg GT, Tsui BMW, Crawford CR, and Edgerton ER. Estimation of Geometric Parameters in Fan Beam Tomography. Phys Med Biol 32(12): 1581-1594, 1987 16. Crawford CR, Gullberg GT, and Tsui BMW. Reconstruction for Fan Beam with an Angular-Dependent Displaced Center-of-Rotation. Med Phys 15(1): 67-71, 1988 17. Saloner D, Hinson WH, Moran PR, and Tsui BMW. MR Flow Imaging in Projection through a Stationary Surround. J Comp Ass Tomogr 12(1): 122-129, 1988 18. Tsui BMW, Hu HB, Gilland DR, and Gullberg GT. Implementation of Simultaneous Attenuation and Detector Response Correction in SPECT. IEEE Trans Nucl Sci, Vol NS-35 (1): 778-783, 1988 19. Gilland DR+, Tsui BMW, Perry JR, McCartney WH, and Berg J. Optimum Filter Function for SPECT Imaging. J Nucl Med, 29:643-650, 1988 20. Tsui BMW, Edgerton ER, Gullberg GT, Gilland DR, Perry JR, McCartney WH, and Berg J. Correction of Nonuniform Attenuation in Cardiac SPECT Imaging Using Iterative Reconstruction Algorithms. J Nucl Med 30:497-507, 1989 21. Gullberg GT, Zeng GL, Tsui BMW and Hagius JT. An Iterative Reconstruction Algorithm for Single Photon Emission Computed Tomography with Cone Beam Geometry. Int J of Imag Sys and Techn, Vol. 1, 169-186, 1989 22. Lathrop KA, Tsui BMW, Chen C-T and Harper PV. Multiparameter extrapolation of biodistribution data between species. Health Physics, Vol. 57, Sup. 1, pp 121-126, 1989 23. Koral KF, Swailem FM, Buchbinder S, Clinthorne NH, Rogers WL and Tsui BMW. SPECT dual-energy-window Compton correction: Scatter multiplier required for tumor quantification. J Nucl Med, 31:90-98, 1990 24. Tsui BMW and Gullberg GT. The geometric transfer function for cone and fan beam collimators. Phys Med Biol 35(1): 81-93, 1990 25. Frey EC* and Tsui BMW. Parameterization of Scatter Response Function in SPECT Imaging Using Monte Carlo Simulation. IEEE Trans Nucl Sci, NS-37(3):1308-1315, 1990 26. Gullberg GT, Tsui BMW, Crawford CR, Ballard JG and Hagius JT. Estimation of Geometrical Parameters and Collimator Evaluation for Cone Beam Tomography. Med Phys, 17(2): 264-272, 1990 27. Frey EC* and Tsui BMW. Spatial properties of the scatter response function in SPECT. IEEE Trans Nucl Sci, NS-38 (2): 789-794, 1991 28. Zeng GL, Gullberg GT, Terry JA and Tsui BMW. Three-dimensional iterative reconstruction algorithms with attenuation and geometric point response correction. IEEE Trans Nucl Sci, NS-38 (2): 693-702, 1991 29. Tsui BMW, Zhao XD*, Frey EC and Gullberg GT. Comparison between ML-EM and WLS-CG Algorithms for SPECT image reconstruction. IEEE Trans Nucl Sci, NS-38 (6): 1766-1772, 1991 30. Gilland DR+, Tsui BMW, Metz CE, Jaszczak RJ and Perry JR. An evaluation of maximum likelihood-EM reconstruction for SPECT by ROC analysis. J Nucl Med, 33:451-457, 1992 31. Lalush DS* and Tsui BMW. Simulation evaluation of Gibbs prior distributions for use in maximum a posteriori SPECT reconstructions. IEEE Trans Med Imag, 11(2): 267-275, 1992 32. Cao ZJ* and Tsui BMW. Performance characteristics of transmission imaging using sheet source with parallel-hole collimation. Med Phys, 19(5): 1205-1212, 1992 33. Frey EC*, Tsui BMW and Perry JR. Simultaneous acqusition of emission and transmission data for improved Tl-201 cardiac SPECT imaging using a Tc-99m transmission source. J Nucl Med, 33(12): 2238-2245, 1992 34. Lalush DS* and Tsui BMW. Attenuation and detector response compensations used with Gibbs prior distributions for maximum a posteriori SPECT reconstruction. IEEE Trans Nucl Sci, 39:1454-1459, 1992. 35. Li J, Jaszczak RJ, Greer KL, Coleman RE, Cao ZJ and Tsui BMW. Direct cone beam SPECT reconstruction with camera tilt. Phys Med Biol, 38:241-258, 1993 36. Tsui BMW, Zhao XD*, Cao ZJ and Frey EC. Reconstruction methods for quantitative brain SPECT. IEEE Trans Nucl Sci, Vol 40(2): 214-220, 1993 37. Lalush DS* and Tsui BMW. A generalized Gibbs prior for maximum a posteriori reconstruction in SPECT. Phys Med Biol 38: 729-741, 1993 38. Cao ZJ* and Tsui BMW. A fully three-dimensional reconstruction algorithm with non-stationary filter for improved single-orbit cone beam SPECT. IEEE Trans Nucl Sci, NS-40 (3): 280-287, 1993 39. Frey EC and Tsui BMW. A practical method for incorporating scatter in a projector-backprojector for accurate scatter compensation in SPECT. IEEE Trans Nucl Sci, NS-40 (4): 1107-1116, 1993 40. Cao ZJ* and Tsui BMW. Improved image quality for asymmetric double-focal cone-beam SPECT. IEEE Trans Nucl Sci, NS-40 (4): 1145-1148, 1993 41. Frey EC, ZW Ju and Tsui BMW. A fast projector-backprojector pair modeling the asymmetric, spatially varying scatter response function for scatter compensation in SPECT imaging. IEEE Trans Nucl Sci, NS-40 (4): 1192-1197, 1993 42. Wilson DW+ and Tsui BMW. Noise properties of filtered-backprojectin and ML-EM reconstructed emission tomographic images. IEEE Trans Nucl Sci, NS-40 (4): 1198-1203, 1993 43. Hasegawa BH, Lang TF, Brown JK, Gingold EL, Reily SM, Blankespoor SC, Liew SC, Tsui BMW and Ramanathan C. Object-specific attenuation correction of SPECT with correlated dual-energy X-ray CT. IEEE Trans Nucl Sci, NS-40 (4): 1242-1252, 1993 44. Tsui BMW, Terry JA+ and Gullberg GT. Evaluation of cardiac cone-beam SPECT using observer performance experiments and ROC analysis. Invest Radiol, 28(12): 1101-1112, 1993 45. Tsui BMW, Zhao XD*, Frey EC and McCartney WH. Quantitative SPECT: Basics and Clinical Considerations. Seminar in Nuclear Medicine, Vol XXIV, No 1 (January), pp 38-65, 1994 46. Tsui BMW, Zhao XD*. Practical iterative reconstruction methods for quantitative cardiac SPECT image reconstruction. IEEE Trans Nucl Sci, 40(1): 325:330, 1994 47. Tsui BMW, Frey EC, Zhao XD*, Lalush DS*, Johnston RE and McCartney WH. The importance and implementation of accurate three-dimensional compensation methods for quantitative SPECT. Phys Med Biol, 39(3): 509-530, 1994 48. Barrett HH, Wilson DW+ and Tsui BMW. Noise properties of the EM algorithm: I. Theory. Phys Med Biol, 39(5): 833-846, 1994 49. Wilson DW+, Barrett HH and Tsui BMW. Noise properties of the EM algorithm: II. Monte Carlo Simulations. Phys Med Biol, 39(5): 847-871, 1994 50. Lalush DS* and Tsui BMW. Improving the convergence of iterative filtered backprojection algorithms. Med Phys, 21(8): 1283-1286, 1994 51. Cao ZJ and Tsui BMW. A filtering technique to compensate for detector response in converging-beam SPECT reconstruction. Phys Med Biol, 39:1281-1293, 1994 52. Beekman FJ, Frey EC, Kamphuis C, Tsui BMW and Viergever MA. A new phantom for fast determination of the scatter response of a gamma camera. IEEE Trans Nucl Sci, 41(4): 1481-1488, 1994 53. Frey EC and Tsui BMW. Modeling the scatter response function in inhomogeneous scattering media for SPECT. IEEE Trans Nucl Sci, 41(4): 1585-1593, 1994 54. Cao ZJ, Frey EC and Tsui BMW. A scatter model for parallel and converging beam SPECT based on the Klein-Nishina formula. IEEE Trans Nucl Sci, 41(4): 1594-1600, 1994 55. LaCroix KJ+, Tsui BMW, Hasegawa BH and Brown JK. Investigation of the use of x-ray CT images for attenuation compensation in SPECT. IEEE Trans Nucl Sci, 41(6): 2793-2799, 1994 56. Zhao XD*, Tsui BMW, Gregoriou GK*, Li J+, Lalush DS* and Eisner RL. Evaluation of corrective reconstruction methods using a 3D cardiac-torso phantom and bulls-eye's plots. IEEE Trans Nucl Sci, 41(6): 2831-2837, 1994 57. Tsui BMW, Zhao XD*, Gregoriou GK*, Lalush DS*, Frey EC, Johnson RE and McCartney. Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy. IEEE Trans Nucl Sci, 41(6): 2838-2844, 1994 58. Lalush DS and Tsui BMW. A fast and stable maximum a posteriori conjuate gradient reconstruction algorithm. Med. Phys. 22(8): 1273-1284, 1995 59. Frey EC and Tsui BMW. A comparison of Gd-153 and Co-57 as tranmission sources for simultaneous TCT and Tl-201 SPECT. IEEE Trans Nucl Sci, 42(4): 1201-1206, 1995 60. Li J+, Tsui BMW, Welch A, Frey EC and Gullberg GT. Energy window optimization in simultaneous Technetium-99m TCT and Thallium-201 SPECT data acquisition. IEEE Trans Nucl Sci, 42(4): 1207-1213, 1995 61. Gregoriou GK*, Tsui BMW and Gullberg GT. Evaluation of the effect of reconstructed image pixel size on defect detectability in Tl-201 fan-beam SPECT by an observer performance study IEEE Trans Nucl Sci, 42(4): 1267-1275, and 1995 62. LaCroix KJ+, Tsui BMW and Hasegawa BH. Comparison of 180o and 360o iterative reconstruction with non-uniform attenuation compensation for SPECT. IEEE Trans Nucl Sci, 42(4): 1276-1281, 1995 63. DiBella EVR, Eisner RL, Schmarkey LS, Barclay AB, Patterson RE, Nowak DJ, Lalush DS and Tsui BMW. Heterogeneity of SPECT bull’s-eyes in normal dogs: Comparison of attenuation compensation algorithms. IEEE Trans Nucl Sci, 42(4): 1290-1296, 1995 64. Ju Z-W, Frey EC and Tsui BMW. Fast distributed 3-D iterative reconstruction for quantitative SPECT. IEEE Trans Nucl Sci, 42(4): 1301-1309, 1995 65. King MA, Tsui BMW and Pan T-S. Attenuation compensation for cardiac SPECT imaging: Part 1. Impact of attenuation and methods of estimating attenuation maps. J Nucl Cardiol, 2(6): 513-524, 1995 66. Tsui BMW. Physics of SPECT. RadioGraphics 16:173-183, 1996 67. King MA, Tsui BMW, Pan T-S, Glick SJ and Soares EJ. Attenuation compensation for cardiac SPECT imaging: Part 2. Attenuation compensation algorithms. J Nucl Cardiol, 3(1): 55-63, 1996 68. King MA, Xia W, deVries DJ, Pan T-S, Villegas BJ, Dahlberg S, Tsui BMW, Ljungberg MH and Morgan HT. A Monte Carlo Investigation of artifacts caused by liver uptake in SPECT perfursion imaging with Tc-99m labelled agents. J Nucl Cardiol, 3(1): 18-29, 1996 69. Kadrmas DJ, Frey EC and Tsui, BMW. An SVD investigation of modeling scatter in multiple energy windows for improved SPECT images. IEEE Trans Nucl Sci, 43(4): 2275-2284, 1996 70. Pan T-S, Tsui BMW and Byrne CL. Choice of initial conditions in the ML reconstruction of fan-beam transmission with truncated projection data. IEEE Trans Med Imag, 16(4): 426-438, 1997 71. Pretorius PH, Xia W. King MA, Tsui BMW, Pan T-S and Villegas BJ. Evaluation of right and left ventricular volume and ejection fraction using a mathematical cardiac torso phantom for gated blood pool SPECT. J Nucl Med, 38:1528-1535, 1997 72. De Vries DJ, King MA, Soares EJ, Tsui BMW and Metz CE. Evaluation of the effect of scatter correction on lesion detection in hepatic SPECT imaging. IEEE Trans Nucl Sci, 44(5): 1733-1740, 1997 73. Kadrmas DJ, Frey EC and Tsui BMW. Analysis of the reconstructibility and noise properties of scattered photons in Tc-99m SPECT. Phys Med Biol, 42:2493-2516, 1997 74. Gregoriou GK*, Tsui BMW and Gullberg GT. Effect of truncated projections on defect detection in attenuation compensation fan-beam cardiac SPECT. J Nucl Med, 39:166-175, 1998 75. LaCroix KJ+, Tsui BMW and Hasegawa BH. A comparison of 180o and 360o acquisition for attenuation compensated Tl-201 images acquired on multi-detector SPECT systems. J Nucl Med, 39:562-574, 1998 76. Frey EC, Tsui BMW and Gullberg GT. Improved estimation of the detector response function for converging beam collimators. Phys Med Biol, 43:941-950, 1998 77. Kadrmas DJ, Frey EC, Karimi SS and Tsui BMW. Fast implementations of reconstruction-based scatter scompensation in fully 3D SPECT image reconstruction. Phys Med Biol, 43: 857-874, 1998 78. Lalush DS and Tsui BMW. Block-iterative techniques for fast 4D reconstruction using a priori motion models in gated cardiac SPECT. Phys Med Biol, 43:875-887, 1998 79. Achtert A-D, King MA, Dahlberg ST, Pretorius, PH, LaCroix KJ and Tsui, BMW. An investigation of the estimation of EF and cardiac volumes by a quantitative gated SPECT software package in simulated gated SPECT perfusion images. J Nucl Cardiol, 5(2):144-152, 1998 80. Lalush DS and Tsui BMW. Mean-Variance Analysis of Block-Iterative Reconstruction Algorithms Modeling 3D Detector Response in SPECT. IEEE TNS, 45(3): 1280-1287, 1998 81. Jang S, Jaszczak RJ, Tsui BMW, Metz CE, Gilland DR, Turkington TG and Colemen RE. ROC evaluation of SPECT myocardial lesion detectability with and without single iteration non-uniform Chang attenuation compensation using an anthropomorphic female phantom. IEEE Trans Nucl Sci, 45(4): 2080-2088, 1998 82. Tsui BMW, Wessell DE+, Zhao, XD, Wang WT, Lewis DP and Frey EC. Imaging characteristics of scintimammography using parallel-hole and pinhole collimators. IEEE Trans Nucl Sci, 45(4): 2155-2161, 1998 83. Kadrmas DJ, Frey EC and Tsui BMW. Application of reconstruction-based scatter compensation to Tl-201 SPECT: Implementations for reduced reconstructed image noise. IEEE Trans Med Imaging, 17(3): 325-333,1998 84. Tsui BMW, Frey EC, LaCroix KJ+, Lalush DS, McCartney WH, King MA and Gullberg GT. Quantitative Myocardial Perfusion SPECT. J Nucl Cardiol, 5(5): 507-522, 1998 85. Lewis DP+ Tsui BMW and Moran PR. Velocity Sensitivity of Slice Selective Excitation. Mag. Res. Imag, 16(8): 907-916, 1998 86. Wollenweber SD*, Tsui BMW, Lalush DS, Frey EC and Gullberg GT. Evaluation of Myocardial Defect Detection Between Parallel-hole and Fan-beam SPECT Using the Hotelling Trace, IEEE Trans Nucl Sci, 45(4): 2205-2210, 1998. 87. Segars WP+, Lalush DS and Tsui BMW. A realistic spline-based dynamic heart phantom. IEEE Trans Nucl Sci, 46(3):503-506, 1999. 88. Kadrmas DJ, Frey EC and Tsui BMW. Simultaneous Technetium99m/Thallium-201 SPECT imaging with model-based compensation for cross-contamination effects. Phys Med Biol, 44:1843-1860, 1999. 89. Pretorius PH, King MA, Tsui BMW, LaCroix KJ* and Xia W. A mathematical model of motion of the heart for use in generating source and attenuation maps for simulating emission imaging. Med Phys, 26(11): 2323-2332, 1999. 90. de Vries DJ, King MA, Soares EJ, Tsui BMW and Metz CE. Effects of scatter subtraction on detection and quantitation in hepatic SPECT, J Nucl Med, 40:1011-1023, 1999. 91. LaCroix KJ*, Tsui BMW, Frey EC and Jaszczak RJ. An ROC evaluation of iterative reconstruction with attenuation compensation in Tc-99m-Sestamibi myocardial SPECT images. J Nucl Med 41(3): 502-513, 2000. 92. LaCroix KJ* and Tsui BMW. Investigation of 90o Dual-Camera Half-Fanbeam Collimation for Myocardial SPECT Imaging. IEEE Trans Nucl Sci, 46(6): 2085-2092, 1999. 93. Lalush DS, Tsui BMW. Performance of Ordered-Subset Reconstruction Algorithms under Conditions of Extreme Attenuation and Truncation in Myocardial SPECT. J Nucl Med 2000, 41(4): 737-744. 94. Lalush DS, Frey EC and Tsui BMW. Fast Maximum Entropy Approximation in SPECT Using the RBI-MAP Algorithm. IEEE Trans. Med. Imaging, 19(4): 286-294, 2000. 95. DS Lalush and Tsui BMW. Fast Transmission CT Reconstruction for SPECT Using a Block-Iterative Algorithm. IEEE Trans Nucl Sci, 47(3): 1123-1129, 2000. 96. Tsui BMW, Segars WP+, Lalush DS. Effects of Upward Creep and Respiratory Motions in Myocardial SPECT. IEEE Trans Nucl Sci, 47(3): 1192-1195, 2000. 97. Segars WP+, Lalush DS, Tsui BMW. Modeling Respiratory Mechanics in the MCAT and Spline-Based MCAT Phantoms. IEEE Trans Nucl Sci, 48(1): 89-97, 2001. 98. MacDonald LR, Patt BE, Iwanczyk JS, Tsui BMW, Wang Y, Frey EC, Wessell DE, Acton PD and Kung HF. Pinhole SPECT of Mice Using the LumaGEM Gamma Camera. IEEE Trans Nucl Sci, 48(3): 830-836, 2001. 99. Tocharoenchai C, Tsui BMW and Frey EC. Performance characterization of a Siemens E.CAM+ Hybrid PET System. Thai Nuclear Medicine Journal, 1:51-60, 2002.100. Tocharoenchai, Tsui BMW and Frey EC. Factor affecting spatial resolution of a hybrid PET system. Thai Nuclear Medicine Journal, 1:74-80, 2002.101. Sankaran S, Frey, EC, Gilland KL and Tsui BMW. Determination of Optimum Compensation Method Combination and Filter Cutoff Choice in Myocardial SPECT: A Human Observer Study, J Nucl Med., 43: 432-438, 2002.102. Du Y, Frey EC, Wang WT, Tocharoenchai C, Baird WH and Tsui BMW. Combination of MCNP and SimSET for Monte Carlo Simulation of SPECT with Medium and High Energy Photons, IEEE Trans. Nucl. Sci., 49(3): 668-674, 2002. 103. Segars WP* and Tsui BMW. Study of the Efficacy of Respiratory Gating in Myocardial SPECT Using the New 4D NCAT Phantom. IEEE TNS Nucl Sci, Vol. 49(3): 675-679, 2002. 104. Tsui, BMW. Interpreting Results from a Comparative Study of Lesion Detectability for 6 Different PET Systems, J Nucl Med, 43(11): 1555-1556, 2002. 105. Frey EC, Gilland KL* and Tsui BMW. Application of task-based measures of image quality to optimization and evaluation of three-dimensional reconstruction-based compensation methods in myocardial perfusion SPECT. IEEE Transactions on Medical Imaging, 21(9):1040-1050, 2002. 106. Wang WT, Frey EC, Tsui BMW, Tocharoenchai C and Baird WH. Parameterization of Pb X-Ray Contamination in Simultaneous Tl-201 and Tc-99m Dual-Isotope Imaging, IEEE TNS, 49(3): 680-692, 2002. 107. Baird WH, Frey EC, Tsui BMW, Wang YC+, and Wessell DE. Evaluation of Rotating Slant-Hole SPECT Mammography Using Monte-Carlo Simulation Methods, IEEE TNS 50(1): 105-109, 2003. 108. Garrity JM+, Segars WP, Knisley SB and Tsui BMW. Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom. IEEE TNS, 50(3): 378-383, 2003. 109. Du Y, Frey EC, Wang WT and Tsui BMW. Optimization of Acquisition Energy Windows in Simultaneous Tc-99m/I-123 Brain SPECT. IEEE TNS 50(5): 1556-1561, 2003. 110. Song X, Frey EC, Wang WT, Du Y and Tsui BMW. Validation and Evaluation of Model-Based Crosstalk Compensation Method in Simultaneous Tc-99m Stress and Tl-201 Rest Myocardial Perfusion SPECT. IEEE TNS 51(1): 72-79, 2004. 111. He X, Frey EC, Links JM, Gilland KL, Segars WP and Tsui BMW. A Mathematical Observer Study for the Evaluation and Optimization of Compensation Methods for Myocardial SPECT Using a Phantom Population That Realistically Models Patient Variablility. IEEE TNS 51(1): 218-224, 2004. 112. Segars WP, Tsui BMW, Frey EC, Johnson GA and Berr SS. Development of a 4-D digital mouse phantom for molecular imaging research. Molecular Imaging & Biology, Volume 6, Issue 3, May-June 2004, Pages 149-159. 113. Qi Y*, Tsui BMW, Gilland KJ, Frey EC, and Gullberg GT. Evaluation of Parallel and Fan-Beam Data Acquisition Geometries and Strategies for Myocardial SPECT Imaging, IEEE TNS 51(4): 667-672, 2004. 114. Pani R, Pellegrini, R, Cinti MN, Trotta C, Bennati P, Betti M, De Vincentis G, Cusanno F, Garibaldi F, Ridolfi S, Majewski S and Tsui BMW. New Devices for Imaging in Nuclear Medicine, Cancer Biotherapy & Radiopharmaceuticals, 19(1), 121-128, 2004. 115. Tocharoenchai C, Tsui BMW, Frey EC, Wang WT, “Effect of Attenuation Correction on Lesion Detection using a Hybrid PET System”, Journal of the Medical Association of Thailand, 88(1): pp96-102, 2005. 116. Song X, Segars WP, Du Y, Tsui BMW and Frey EC. Fast modeling of the collimator-detector response in Mone Carlo simulation of SPECT imaging using the angular response function, Phys Med Biol 50: 1791-1804, 2005. 117. Tsui BMW and Wang Y. High-Resolution Molecular Imaging Techniques for Cardiovascular Research. J Nucl Cardiol 12:262-267, 2005. 118. Kraitchman DL, Tatsumi M, Gilson WD, Ishimori T, Kedziorek D, Walczak P, Segars WP, Chen HH, Fritzges D, Izbudak I, Young RG, Marcelino M, Pittenger MF, Solaiyappan M, Boston RC, Tsui BMW, Wahl RL and Bulte JWM. Dynamic Imaging of Allogeneic Mesenchymal Stem Cells Trafficking to Myocardial Infarction. Circulation 112:1454-1464, 2005. 119. Du Y, Tsui BMW and Frey EC. Partial volume effect compensation for quantitative brain SPECT imaging, IEEE Trans Med Imag, 2005, in press. 120. Wang WT, Frey EC, Tsui BMW, Lalush DS, and Tocharoenchai C. Optimization of acquisition parameters for simultaneous 201Tl and 99mTc dual-isotope myocardial imaging, IEEE Trans Nucl Sci, 2005 in press. 121. He X, Links JM, Song X, Tsui BMW, and Frey EC. Comparison of penetration and scatter effects on detect contract for GE and siemens LEHR collimators in myocardial perfusion SPECT – A simulation study. IEEE Trans Nucl Sci, 2005, in press. 122. Stumpf MJ, Frey EC, Tsui BMW and Gullberg GT. An investigation of noise characteristics in OSEM reconstruction of fan beam SPECT using a rotating/Warping Projector/Backprojector. submitted to IEEE Trans Nucl Sci, November 2005. 123. He X, Links JM, Tsui BMW and Frey EC. Comparison of 180-degree and 360-degreeacquisition for myocardial perfusion SPECT with compensation for attenuation, detector response, and scatter: Monte Carlo and mathematical observer results. Journal of Nuclear Medicine, submitted. 124. Veress AI, Segars WP, Tsui BMW, Weiss JA and Gullberg GT. Normal and Pathological NCAT Image and Phantom Data Based on Physiologically Realistic Left Ventricle Finite Element Models. Manuscript accepted for publication in IEEE Transactions in Med Imaging, 2005. 125. Wang YC and Tsui BMW. Application of Homogeneous Coordinates in the Development and Implementation of Iterative Reconstruction Algorithms for Pinhole SPECT with Different Data Acquisition Geometries. Manuscript submitted to IEEE Transactions in Medical Imaging, 2005. 126. Xu J, Liu C, Wang Y, Frey EC and Tsui BMW. Quantitative Rotating Multi-Segment Slant-Hole SPECT Mammography with Attenuation and Collimator-Detector Response Compensation. Manuscript submitted to IEEE Transactions in Medical Imaging, 2005. 127. Lee T-S, Segars WP and Tsui BMW. Development and Optimization of a 4D MAP-RBI-EM Reconstruction Algorithm with Space-Time Gibbs Priors for Application to Gated Myocardial Perfusion SPECT. Manuscript submitted to IEEE Transactions in Medical Imaging, 2005. 128. Xu J, Wang Y, Liu C, Frey EC and Tsui BMW. Attenuation correction for rotating multisegment slant-hole SPECT in breast imaging,” submitted to Physica Medica. 129. Segars W, Silva AD, Shao L and Tsui B. CT-PET image fusion using the 4D NCAT phantom with the purpose of attenuation correction. Accepted for publcation, IEEE TNS, 2006.
________________________________________________________________________ + Graduate student under direct supervision * Postdoctoral Fellow/Research Associate under direct supervision B. Non-peer reviewed Articles*** The following 2 manuscripts are in: Proceedings of the Third International Radiopharmaceutical Dosimetry Symposium, Oak Ridge, Tennessee, and October 7-10, 1980. HHS Publication FDA 81-8166, 1981. 1. Tsui BMW, Chen C-T, Yasillo NJ, Ortega CJ, Charleston DB, Harper PV, and Lathrop KA. Description of the Design and Use of a Whole-Body Scanning System for Collection of Quantitative in Vivo Distribution Data in Humans. pp. 138-156, 1981. 2. Tsui BMW, Lathrop KA, and Harper PV. Extrapolation of Tissue Distribution Data for *T1 and *Ga from Animal to Human. pp. 283-291, 1981. 3. Jaszczak RJ, Greer KL, Coleman, RE and Tsui BMW. SPECT Instrumentation: Evaluation of System Performance. In Proceedings of Southeastern Chapter of Society of Nuclear Medicine - Continuing Education Lectures, Simon GH, ed., (Society of Nuclear Medicine, NY), Chapter VIII: 1-14, 1985. 4. Crawford CR, Gullberg GT, and Tsui BMW. Fan Beam Reconstruction for Displayed Center-of-Rotation. In Proceedings of the Seventh Annual Conference of the Engineering in Medicine and Biology Society, IEEE 930-933, 1985. *** The following 2 manuscripts are in: Proceedings of the 11th Annual University of North Carolina Radiology Symposium, 1987. 5. Tsui BMW. Recent Advances in SPECT Imaging. pp. 30-39, 1987. 6. Tsui BMW. Current Status of MRI Imaging. pp. 69-76, 1987. 7. Tsui BMW. Recent Advances in SPECT Instrumentation and Image Processing Techniques. In Proceedings of Southeastern Chapter of Society of Nuclear Medicine - Continuing Education Lectures, E.B. Silberstein, ed. (Society of Nuclear Medicine, NY), pp. XX-1-XX-10, 1987. 8. DiBianca FA, Vance JE, Wagenaar DJ, Fetter JE, Tenney CR, Tsui BMW, Reed MS, McDaniel DL, and Granfors P. Noise Properties of a Kinestic Charge Detector. In Proceedings of Society of Photo-Optical Instrumentation Engineering, 914:212-218, 1988. 9. Tsui BMW, Perry JR, Gilland DR, Interrante VL, Pizer SM, Fuchs H, and McCartney WH. Simultaneous Three-Dimensional Display of Anatomical and Functional Information Obtained With SPECT. In Imaging Hardware and Software for Nuclear Medicine, RE Zimmerman and JM Links eds., AAPM Symposium Proceedings No. 6, (AIP, New York) pp. 197-206, 1988. 10. Gullberg GT and Tsui, BMW. Maximum Entropy Reconstruction With Constraints: Iterative Algorithms for Solving the Primal and Dual Program. In Proceedings of the Tenth International Conference on Information Processing in Medical Image, June 22-26 1987, Utrecht, The Netherlands, (Plenum, New York) pp. 181-199, 1988. 11. Tsui BMW, Zhao XD, Frey EC, Perry JR and Gullberg GT. Acquisition and image reconstruction methods for improved cardiac SPECT imaging. In: Biomedical Engineering: Opening New Doors. (Proceedings of the 1990 Fall Meeting of the Biomedical Engineering Society, Blacksburg, VA, 1990), New York University Press, pp 221-229, 1990. *** The following 2 manuscripts are in: Biomedical Engineering: Opening New Doors. (Proceedings of the 1990 Fall Meeting of the Biomedical Engineering Society, Blacksburg, VA, 1990), New York University Press, 1990. 12. Terry JA+, Tsui BMW, Perry JR, Hendricks JL and Gullberg GT. The design of a mathematical phantom of the upper human torso for use in 3-D SPECT imaging research, pp 185-190, 1990. 13. Ballard JG+, Tsui BMW and Johnston RE. Quantitative evaluation of two SPECT reconstruction techniques. pp 147-154, 1990. 14. Gullberg GT, Zeng GL, Christian PE, Tsui BMW and Morgan HT. Single Photon Emission Computed Tomography of the Heart Using Cone Beam Geometry and Noncircular Detector Rotation. In Information Processing in Medical Imaging, XIth Information Processing in Medical Imaging (IPMI) International Conference, Berkeley, CA, June 19-23, Eds Ortendahl DA and Llacer J, Wiley-Liss, New York, pp 123-138, 1991. *** The following 5 manuscripts are in: Conference Record of the 1990 Nuclear Science Symposium and the Medical Imaging Conference 90, October 23-27, Arlington, VA, 1990. 15. Tsui BMW, Zhao XD, Frey EC and Gullberg GT. Properties of Iterative algorithms in SPECT image reconstruction. pp. 1467-1474, 1990. 16. Frey EC* and Tsui BMW. Spatial properties of the scatter response function in SPECT. pp. 1183-1188, 1990. 17. Lalush DS+ and Tsui BMW. Simulation evaluation of Gibbs prior distributions for use in maximum a posteriori SPECT reconstructions. pp. 1600-1609, 1990. 18. Zeng GL, Gullberg GT, Terry JA and Tsui BMW. Three-dimensional iterative reconstruction algorithms with attenuation and geometric point response correction. pp. 1475-1479, 1990. 19. Reilly SM, Hasegawa BH, Gingold EL, Ramanathan C and Tsui BMW. A computer simulation of simultaneous emission - transmission CT. pp. 1212, 1990. *** The following 5 manuscripts are in: Conference Record of the 1991 Nuclear Science Symposium and the Medical Imaging Conference, November 2-9, Santa Fe, NM, 1991. 20. Tsui BMW, Zhao XD, Cao ZJ* and Frey EC*. Reconstruction methods for quantitative brain SPECT. pp. 1763-1769, 1991. 21. Frey EC* and Tsui BMW. A practical-backprojector modeling attenuation, detector response, and scatter for accurate scatter compensation in SPECT. pp. 1777-1781, 1991. 22. Cao ZJ* and Tsui BMW. Non-stationary filtering technique for improved cone beam SPECT. pp. 1938-1942, 1991. 23. Wilson DW+, Tsui BMW and Terry JA+. Non-stationary noise characteristics for SPECT images. pp. 1736-1740, 1991. 24. Lalush DS+ and Tsui BMW. Attenuation and detector response compensations used with Gibbs prior distributions for maximum a posteriori SPECT reconstruction. pp 1797-1802, 1991. *** The following 2 manuscripts are in: Proceedings of the NATO Advanced Study Institute on the Formation, Handling, and Evaluation of Medical Image, September 12-23, 1988, Porto, Portugal, A.E. Todd-Pokropek and M.A. Viergever eds., NATO ASI Series, F, Springer-Verlag, Heidelberg, 1992 25. Tsui BMW, Hu HB, Gullberg, GT, Gilland DR, Ballard JG, Perry JR, McCartney WH, and Bernstein T. Applications of Iterative Reconstruction Methods in SPECT. pp 503-524, 1992. 26. Gilland DR+, Tsui BMW, Hu HB, and Perry JR. Computed Simulated Cardiac SPECT Data for Use in Evaluating Reconstruction Algorithms. pp 525-538, 1992. *** The following 7 manuscripts are in: Conference Record of the 1992 Nuclear Science Symposium and the Medical Imaging Conference, October 27-31, Orlando, FL, 1992. 27. Lalush DS* and Tsui BMW. Optimization of Gibbs Priors based on Object Size and Contrast for Maximum A Posteriori Reconstruction in SPECT. pp 1023-1025, 1993. 28. Frey EC, Ju ZW and Tsui BMW. A fast projector-backprojector pair modeling the asymmetric, spatially compensation in SPECT imaging. pp 1032-1034, 1993. 29. Frey EC and Tsui BMW. A comparison of scatter compensation methods in SPECT: Subtraction-based Techniques versus iterative reconstruction with an accurate scatter model. pp 1035-1037, 1993. 30. Cao ZJ* and Tsui BMW. Improved image quality for asymmetric double-focal cone beam SPECT. pp 1068-1070, 1993. 31. Cao ZJ* and Tsui BMW. A practical reconstruction algorithm for multifocal cone beam SPECT. pp 1074-1076, 1993. 32. Wilson DW+ and Tsui BMW. Noise properties of filtered-backprojection and ML-EM reconstructed emission tomographic images. pp 1114-1116, 1993. 33. Tsui BMW, Zhao XD*. Practical iterative reconstruction methods for quantitative cardiac SPECT image reconstruction. p 1178, 1993. 34. Zhao XD*, Tsui BMW, Gregoriou GK*, Li J+, Lalush DS* and Eisner RL. Evaluation of corrective reconstruction methods using a 3D cardiac-torso phantom and bulls-eye's plots. pp 1164-1168, 1994. 35. LaCroix KJ+, Tsui BMW, Hasegawa BH and Brown JK. Investigation of the use of x-ray CT images for Attenuation compensation in SPECT. pp 1169-1173, 1994. 36. Lalush DS* and Tsui BMW. MAP-EM and WLS-MAP-CG reconstruction methods for transmission imaging in cardiac SPECT. pp 1174-1178, 1994. 37. Cao ZJ, Frey EC and Tsui BMW. A scatter model for parallel and converging beam SPECT based on the Klein-Nishina formula. pp 1179-1183, 1994. 38. Frey EC and Tsui BMW. Modeling the scatter response function in inhomogeneous scattering media for SPECT. pp 1184-1188, 1994. 39. Wilson DW+ and Tsui BMW. Spatial resolution properties of FB and ML-EM reconstruction methods. pp 1189-1193, 1994. 40. Tsui BMW, Zhao XD*, Gregoriou GK*, Lalush DS*, Frey EC, Johnson RE and McCartney. Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy. pp 1444-1448, 1994. 41. Beekman FJ, Frey EC, Kamphuis C, Tsui BMW and Viergever MA. A new phantom for fast determination of the scatter response of a gamma camera. pp 1847-1851, 1994. 42. Tsui BMW. Single-photon emission computed tomography (SPECT) imaging. In Proceedings of the 1994 IEEE International Conference on Image Processing, November 13-16, Austin, TX, 1994, pp 1031-1035, 1994. *** The following 8 manuscripts are in: Conference Record of the 1994 Nuclear Science Symposium and the Medical Imaging Conference, October 30 - November 5, Norfolk, VA, 1994. 43. Tsui BMW, Lewis DP+ and Li J+. Detection efficiencies of parallel, fan and cone beam collimators for source distributions in an attenuating medium. pp 1145-1149, 1995. 44. LaCroix KJ+, Tsui BMW and Hasegawa BH. Comparison of 180o and 360o iterative reconstruction with non-uniform attenuation compensation for SPECT. pp 1197-1201, 1995. 45. Cao Z and Tsui BMW. A novel SPECT collimation system and related reconstruction algoritum. pp 1266-1269, 1995. 46. Welch A, Gullberg GT, Christian PE, Li J+ and Tsui BMW. An investigation of dual-energy transmission measurements for more accurate non-uniform attenuation compensation in cardiac SPECT. pp 1558-1662, 1995. 47. Frey EC and Tsui BMW. A comparison of Gd-153 and Co-57 as tranmission sources for simultaneous TCT and Tl-201 SPECT. pp 1582-1586, 1995. 48. Li J+, Tsui BMW, Welch A, Frey EC and Gullberg GT. Energy window optimization in simultaneous Technetium-99m TCT and Thallium-201 SPECT data acquisition. pp 1587-1594, 1995. 49. DiBella EVR, Eisner RL, Schmarkey LS, Barclay AB, Patterson RE, Nowak DJ, Lalush DS and Tsui BMW. Heterogeneity of SPECT bull’s-eyes in normal dogs: Comparison of attenuation compensation algorithms. pp 1725-1729, 1995. 50. Gregoriou GK*, Tsui BMW and Gullberg GT. Evaluation of the effect of reconstructed image pixel size on defect detectability in Tl-201 fan-beam SPECT by an observer performance study. pp 1907-1914, 1995. *** The following 3 manuscripts are in: Proceedings of the 1995 International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, July 4-6, Aix-les-Bains, Savoie, France, 1995. 51. Tsui BMW, Zhao XD*, Frey EC, JU Z-W and Gullberg GT. Characteristics of reconstructed point response in three-dimensional spatially variant detector response compensaiton in SPECT. pp 161-168, 1995. 52. Lalush DS and Tsui BMW. Space-time Gibbs priors applied to gated SPECT myocardial perfusion studies. pp. 37-42, 1995. 53. Frey EC, Ju Z-W and Tsui BMW. Reducing reconstruction time for iterative 3-D reconstruction scatter compensation. pp. 201-206, 1995. 54. Tsui BMW. Attenuation Correction in SPECT. Proceedings of the Southeastern Chapter Meeting of the Society of Nuclear Medicine, October 20-22, 1995, Orlando, FL, p. XIX-1 to XIX-7 *** The following 7 manuscripts are in: Conference Record of the 1995 Nuclear Science Symposium and the Medical Imaging Conference, October 21 - 28, San Francisco, CA, 1995. 55. Kadrmas DJ, Frey EC and Tsui BMW. An SVD investigation of modeling scatter in multiple energy windows for improved SPECT images. pp 1097-1101. 56. Tsui BMW, Zhao XD* and Frey EC. 3D detector response compensation in SPECT using multigrid iteration reconstruction methods. pp. 1151-1155. 57. Li J+, Tsui BMW, Frey EC and Gullberg GT. Deconvolution scatter compensation for Thallium-201 fan-beam cardiac SPECT. pp 1175-1179. 58. Pan T-S, Tsui BMW and Byrne CL. Choice of initial conditions in the ML reconstruction for transmission CT with truncated projection data. pp 1232-1236. 59. Lalush DS and Tsui BMW. The importance of preconditioners in fast Poisson-based iterative reconstruction algorithms for SPECT. pp 1326-1330. 60. Gregoriou GK*, Tsui BMW, Frey EC and Lalush DS. Artifacts and data sampling requirement in transmission CT reconstruction with truncated projection data. pp 1336-1340. 61. deVries DJ, King MA, Tsui BMW and Metz CE. Evaluation of the effect of scatter correction on lesion detection in hepatic SPECT imaging. pp 1665-1669. 62. Tsui BMW, McCartney WH, Lewis DP+, Lalush DS, Frey EC and Perry JR. Attenuation and scatter corrections: Update and pitfalls. In “The Clinical Value of Nuclear Medicine”, Proceedings of the Southern Chapter, Proceedings of the 37th Annual Meeting, Atlanta, GA, October 18-20, 1996, pp XV-1 to XV-11. *** The following 7 manuscripts are in: Conference Record of the 1996 Nuclear Science Symposium and the Medical Imaging Conference, November 3 - 9, Anaheim, CA, 1996. 63. Frey EC and Tsui BMW. A new method for modeling the spatially variant, object-dependent scatter response function in SPECT. pp 1082-1086. 64. Wessell DE+, Kadrmas DJ, Frey EC and Tsui BMW. Limited angle tomographic breast imaging: A comparison of parallel beam and pinhole collimation. pp 1104-1108. 65. Tsui BMW, Wessell DE, Zhao XD, Frey EC, McCartney WH and Peterson NP. Evaluation of collimation and imaging configuration in scintimammography. pp 1377-1381. 66. Lalush DS, Karimi S and Tsui BMW. Convergence and resolution recovery of block iterative EM algorithms modeling 3D detector response in SPECT. pp 1618-1622. 67. Tsui BMW, Lewis DP+, Frey EC and Lalush DS. Reconstruction of truncated TCT and SPECT data from a right angle dual comera system for myocardial SPECT. pp 1643-1647. 68. Lalush DS and Tsui BMW. A Priori motion models for four-dimensional reconstruction in gated cardiac SPECT. pp 1923-1927. 69. Kadrmas DJ, Frey EC and Tsui BMW. Application of reconstruction-based scatter compensation to Tl-201 SPECT. pp 1663-1667. *** The following 6 manuscripts are in: Conference Record of the 1997 Nuclear Science Symposium and the Medical Imaging Conference, November 9 - 15, Albuquerque, NM, 1997. 70. Wollenweber SD*, Tsui BMW, Lalush DS, Frey EC and Gullberg GT. Evaluation of Myocardial Defect Detection between Parallel-hole and Fan-beam SPECT Using the Hotelling Trace. pp 1428-1432 71. Lalush DS and Tsui BMW. Mean-Variance Analysis of Block-Iterative Reconstruction Algorithms Modeling 3D Detector Response in SPECT. pp 1566-1570 72. Jang S, Jaszczak RJ, Tsui BMW, Metz CE, Gilland DR, Turkington TG and Coleman RE. ROC Evaluation of SPECT Myocardial Lesion Detectability with and without Non-Uniform Attenuation Compensation Using an Anthromorphic Female Phantom. pp 998-1002 73. Lewis DP+ and Tsui BMW. Estimation of Half Fan-Beam Collimator Parameters for Brain SPECT with an L-Shaped Dual Camera SPECT System. pp 1052- 74. Wessell DE+, Tsui BMW, Frey EC and Karimi SS. Rotating Quadrant Slant-Hole SPECT Scintimammography: An Initial Investigation. pp 1145-1149 75. Tsui BMW, Wessell DE+, Zhao XD*, Wang WT+, Lewis DP+ and Frey EC. Imaging Characteristics of Scintimammography Using Parallel-Hole and Pinhole Collimators. pp 1323-1327 76. Pretorius PH, King MA, Tsui BMW, LaCroix KJ and Xia W. A dynamic heart model for the Mathematical Cardiac Torso (MCAT) phantom to represent the invariant total heart volume. Proceeding of the SPIE Medical Imaging Conference (Physiology and Function), 153-163. 77. Tsui BMW and Frey EC. Three-dimensional imaging reconstruction methods for quantitative myocaridal perfusion SPECT. Proceeding of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Hong Kong, October 29 – November 1, 1998. Vol. 20, I-502-505 *** The following 8 manuscripts are in: Conference Record of the 1998 Nuclear Science Symposium and the Medical Imaging Conference, November 8 – 14, 1998, Toronto, Ontario, Canada 78. Lalush DS, Frey EC, Tsui BMW. Fast Maximum Entropy Approximation in SPECT Using the RBI-MAP Algorithm. pp. 1157-1164 79. Segars WP+, Lalush DS, Tsui BMW. A Realistic Spine-Based Dynamic Heart Phantom. pp. 1175-1179 80. LaCroix KJ*, Tsui BMW. Investigation of 90-degree Dual-Detector Half-Fanbeam Collimation for Myocardial SPECT Imaging. pp. 1189-1194 80. Wang WT+, Tsui BMW, Frey EC, Wessell DE+. Comparison of an Analytical and an Iterative Based Collimator-Detector Response Compensation Method in SPECT. pp. 1382-1386 81. Tocharoenchai C+, Tsui BMW, Lewis DP+, Frey EC, Zhao XD*. Compensation for the Response Function of a Medium Energy Collimator in Ga-67 Planar and SPECT Imaging. pp. 1405-1408 82. Wollenweber SD*, Tsui BMW, Rempel TD, Simcic V. Initial Characterization of the Siemens ECAM+: A Dual-Detector Camera With Coincidence Imaging Capability. pp. 1470-1476 83. Lewis DP+, Tsui BMW, Tocharoenchai C+, Frey EC. Characterization of Medium and High Energy Collimators Using Ray-Tracing and Monte Carlo Methods. pp. 2026-2027 84. Wollenweber SD*, Tsui BMW, Lalush DS, Frey EC, LaCroix KJ*, Gullberg GT. Comparison of Radially-Symmetric Versus Oriented Channel Models Using Channelized Hotelling Observers for Myocardial Defect Detection in Parallel-Hole SPECT. pp. 2090-2094 85. Tsui BMW, Wessell DE+, Peterson NP, Zhao XD*, Le PT+, McCartney WH. Improved Scintimammography using Pinhole Collimation. Scientific Program of the 84th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Chicago, IL, November 29-December 4, 1998. p. 441 *** The following 7 manuscripts are in: Conference Record of the 1999 Nuclear Science Symposium and the Medical Imaging Conference, October 24-30, 1999, Seattle, Washington 86. Wang WT+, Frey EC, Tsui BMW. Parameterization of Pb X-Ray Contamination in Simultaneous Tl-201 and Tc-99m Dual Isotope SPECT. p 116 on CDROM 87. Segars WP+, Lalush DS, Tsui BMW. Modeling Respiratory Mechanics in the MCAT and Spline-Based MCAT Phantoms. p 117 on CDROM 88. Tsui BMW, Segars WP+, Lalush DS. Effects of Upward Creep and Respiratory Motions in Myocardial SPECT. p 127 on CDROM 89. Tsui BMW, Zhao XD, Wang WT+, Tocharoenchai C+, Yang Y, Frey EC. Characterization of Medium and High Energy Collimators for SPECT. p 129 on CDROM 90. Lalush DS, Tsui BMW. Fast Transmission CT Reconstruction for SPECT Using a Block-Iterative Algorithm. p 132 on CDROM 91. Lalush DS, Segars WP+, Tsui BMW. A Unified Approach to 4D Gated Myocardial SPECT Reconstruction. 92. Nowak R, Kolaczyk E, Lalush DS, Tsui BMW. A Bayesian Multiscale Framework for SPECT. p 124 on CD ROM 93. LaCroix KJ*, Tsui BMW, Frey EC. Oriented vs. Non-oriented Frequency Channels for the Hotelling Observer: A Comparison with Human Observers. p 131 on CDROM *** The following 7 manuscripts are in: Conference Record of the 2000 Nuclear Science Symposium and Medical Imaging Conference, October 15-20, 2000, Lyon, France 94. Frey EC, Gilland KJ* and Tsui BMW. Optimization and Evaluation of Reconstruction-Based Compensation Methods in Myocardial Perfusion SPECT Using the Channelized Hotelling Observer. P. 1619 on CDROM (abstract only) 95. Wang Y+, Wessell DE, Frey EC and Tsui BMW. A 3D Filtered Back-Projection Algorithm for SPECT Using a Multi-Segment Rotating Slant-Hole Collimator. P. 1832-1834 on CDROM 96. Sawyer SA, Frey EC, Gilland KL, Tsui BMW and Gormley J. Performance Evaluation of a Small Field-of-View Camera for Myocardial Perfusion SPECT Using a Channelized Hotelling Observer. P. 2518-2521 on CDROM 97. Segars WP+, Lalush DS and Tsui BMW. Development of an Interactive Software Application to Model Patient Populations in the Spline-Based MCAT Phantom. P. 2527-2531 on CDROM 98. Tsui BMW, Zhao XD*, Sayeram S+, Frey EC, Falen SW and McCartney WH. Evaluation of Collimator-Detector Response Compensation in Tumor SPECT Using Medium and High Energy Collimators. P. 2253 on CDROM (abstract only) 99. Wessell DE+, Frey EC and Tsui BMW. The Geometric Transfer Function for Slant-Hole Collimators. P. 2733 on CDROM (abstract only) 100. MacDonald LR, Iwanczyk JA, Patt BE, Tull CR, Acton PD, Kung HF and Tsui BMW. Development of New High Resolution Detectors for Small Animal SPECT Imaging. P. 2673 on CDROM (abstract only) *** The following 9 manuscripts are in: Conference Record of the 2001 Nuclear Science Symposium and Medical Imaging Conference, November 4-10, 2001, San Diego, CA 101. Segars WP* and Tsui BMW. Study of the Efficacy of Respiratory Gating in Myocardial SPECT Using the New 4D NCAT Phantom. P. 812 on CD ROM. 102. Baird WH, Frey EC, Tsui BMW, Wang YC+, and Wessell DE. Evaluation of Rotating Slant-Hole SPECT Mammography Using Monte-Carlo Simulation Methods, P. 812 on CDROM 103. Qi Y*, Tsui, BMW, Gilland KJ, Frey EC, and Gullberg GT. Evaluation of Data Acquisition Geometries and Strategies for Myocardial SPECT Imaging, P. 812 on CDROM. 104. Wang WT, Frey EC, Tsui BMW and Tocharoenchai C. A model-based crosstalk compensation method for simultaneous Tl-201 and Tc-99m dual isotope myocardial SPECT imaging. P. 812 on CDROM 105. Wang Y+, Tsui BMW, Baird WH, Frey EC and Wessell DE, Investigation of Acquisition and Image Reconstruction Parameters for Rotating Multi-Segment Slant-Hole SPECT, P. 812 on CDROM 106. Du Y, Frey EC, Wang WT, Tocharoenchai C, Baird WH and Tsui BMW. Combination of MCNP and SimSET for Monte Carlo Simulation of SPECT with Medium and High Energy Photons, P. 812 on CDROM. 107. Song X, Frey EC, Wang Y+ and Tsui BMW. Development of a MicroCT System for Small Animal Imaging, P. 812 on CD ROM. 108. McElroy DP, MacDonald LR, Beekman FJ, Wang Y, Patt BE, Iwanczyk JS, Tsui BMW and Hoffman EJ. Evaluation of A-SPECT: A Desktop Pinhole SPECT System for Small Animal Imaging. P. 812 on CD ROM 109. Smyczynski MS, Segars WP*, Narayanan MV, Pretorius PH, Gifford HC, Farncombe TH, Hoffman EA, Tsui BMW and King MA. Modeling the Respiratory Motion of Solitary Pulminary Nodules for Investigating SPECT Tumor Imaging. P. 812 on CD ROM. 110. Tocharoenchai C, Tsui BMW, Lalush DS, Frey EC, Gilland KJ and Wang WT. Proceedings of the First Asia Oceania Congress of Medical Physics (AOCMP), November 14-16, 2001, Bangkok, Thailand, pp 211-216, 2001. 111. Faber TL, Garcia EV, Lalush DS, Segars WP*, Tsui BMW. Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom. Visualization, Display, and Image Guided Procedures, Seong Ki Mun, editor. Proceedings SPIE 4319:22-26, 2001. *** The following 10 manuscripts are in: Conference Record of the 2002 Nuclear Science Symposium and Medical Imaging Conference, November 10-16, 2002, Norfolk, VA. 112. He X, Frey EC, Gilland KL, Segars WP, and Tsui BMW. Evaluation and optimization of compensation methods for myocardial SPECT using a set of realistic phantoms that include patient variability. P. 582 on CDROM. 113. Smyczynski MS, Gifford HC, Farncombe TH, Segars WP, Tsui BMW and King MA. Impact of respiratory motion on the detection of solitary pulmonary nodules with SPECT imaging of NeoTect. P. 583 on CDROM. 114. Tsui BMW, Du Y, Segars WP, Zhao X*, and Frey EC. Fast Monte Carlo simulation method for medium- and high-energy SPECT. P. 583 on CDROM. 115. Zhu Z+, Tsui BMW, and Segars WP. A simulation study of the effect of gating scheme on respiratory motion blurring in FDG lung PET. P. 582 on CDROM. 116. Segars WP, Tsui BMW, Da Silva AJ, and Shao L. CT-PET image fusion using the 4D NCAT phantom with the purpose of attenuation correction. P. 582 on CDROM. 117. Garrity JM+, Segars WP, Knisley SB and Tsui BMW. Development of a dynamic model for the lung lobes and airway tree in the NCAT phantom. P. 583 on CDROM. 118. Qi YJ*, Tsui BMW, Yoder B+ and Frey EC. Characteristics of Compact Detectors Based on Pixellated NaI(Tl) Cyrstal Arrays. P. 582 on CDROM. 119. Wang Y+, Tsui BMW and Baird WH. Optimal Camera Placement for Cardiac Imaging using Rotating Multi-Segment Slant Hole Single Photon Emission Computed Tomography. P. 582 on CDROM. 120. Du Y, Frey EC, Wang WT and Tsui BMW. Optimization of Acquisition Energy Windows in Simultaneous Tc-99m/I-123 Brain SPECT. P. 583 on CDROM. 121. Song X, Frey EC, Wang WT, Du Y and Tsui BMW. Validation and Evaluation of Model-Based Cross-Talk Compensation Method in Simultaneous Tc-99m Stress and Tl-201 Rest Myocardial Perfusion SPECT. P. 583 on CDROM. *** The following 11 manuscripts are in: Conference Record of the 2003 Nuclear Science Symposium and Medical Imaging Conference, November 19-26, 2003, Portland, OR. 122. Lee TS+, Segars WP and Tsui BMW. A Study of the Effect of Cardiac Gating in Myocardial SPECT using the 4D NCAT. P. 1172 on CDROM. 123. He B, Frey EC, Beck TJ, Sawyer SA and Tsui BMW. Measurement and Deconvolution of Glare in a Micro-CT Scanner for In-Vivo Small Animal Imaging. P. 1172 on CDROM. 124. He X, Frey EC, Links JM, Song XY and Tsui BMW. Comparison of Penetration and Scatter Effects on Defect Contrast for GE and Siemens LEHR Collimators in Myocardial Perfusion SPECT – A Simulation Study. P. 1173 on CDROM. 125. Gilland KL, Qi Y*, Tsui BMW and Gullberg GT. Comparison of Channelized Hotelling and Human Observers in Determining Optimum OSEM Reconstruction Parameters for Myocardial SPECT. P. 1173 on CDROM. 126. Sawyer SA, Frey EC, He B, Wang Y and Tsui BMW. Implementation of Short Scan Reconstruction with Compensation for Geometric Alignment for a Micro-CT System. P. 1173 on CDROM. 127. Sayeram S+, Tsui BMW, Zhao XD* and Frey EC. Performance Evaluation of Three Different SPECT Systems used in In-111 Prostascint SPECT Imaging. P. 1173 on CDROM. 128. Segars WP, Tsui BMW, Frey EC and Fishman EK. Extension of the 4D NCAT Phantom to Dynamic X-Ray CT Simulation. P. 1173 on CDROM. 129. Wojcik R, Goode AR, Smith MF, Beller GA, Ellman PI, Majewski S, Qi YJ, Tsui BMW, Wang Y, Weisenberger AG and Glover DK. Dedicated Small Field of View SPECT System Based on a 5” PSPMT and Crystal Scintillator Array for High Resolution Small Animal Cardiac Imaging. P. 1173 on CDROM. 130. Pellegrini R, Pani R, Cinti MN, Trotta C, Iurlaro G, Betti M, Bennati P, Cusanno F, Garibaldi F, Ridolfi S, Mattioli M, Majewski S and Tsui BMW. Design of Compact Pinhole SPECT System based on Flat Panel PMT. P. 1173 on CDROM. 131. Qi Y*, Tsui BMW, Wang Y+, Yoder B+, Wojcik R and Majewski S. Performance Characteristics of a New Modular Camera Based on Pixellated Crystal for High Resolution Pinhole SPECT with Comparison to a Standard Camera with Continuous Crystal. 132. Song XY, Frey EC, He X, Segars WP and Tsui BMW. A Mathematical Observer Study for Evaluation of a Model-based Compensation Method for Crosstalk in Simultaneous Dual Isotope SPECT. *** The following 10 manuscripts are in: Conference Record of the 2004 IEEE Nuclear Science Symposium and Medical Imaging Conference, October 16-22, 2004, Rome, Italy 132. He X, Frey EC, Links JM, Tsui BMW. Describing Three-Class Task Performance: Three-Class Volume under ROC Surface (VUS) and Three-Class Hotelling Trace (3-HT) as Figures of Merit. 133. He B, Frey EC, Tsui BMW. Caomparison of Conventional and Model-Based Quantitative Planar Image Processing Methods for Organ Activity Estimation Using In-111 Agents. 134. Mok SP, Tsui BMW, Wang Y, Qi Y, Du Y, Segars WP, Yoder BC, Frey EC. Development and Validation of a Monte Carlo Simulation Tool for Multi-Pinhole MicroSPECT. 135. Lee TS, Segars WP, Tsui BMW. Application of 4D RBI_MAO Reconstruction Algorithm for Gated Cardiac SPECT. 136. Gilland KL, Tsui BMW, Qi Y. Comparison of Rotationally Symmetric and Oriented Channels for the Hotelling Observer for Myocardial SPECT Images. 137. Tsui BMW, Wang Y, Mok SP, Segars WP. Design Parameters of High Performance Multi-Pinhole SPECT. 138. Stumpf MJ, Frey EC, Tsui BMW, Gullberg GT. Improved Noise Characteristics in OSEM Reconstruction of Fan Beam SPECT Using a Rotating/Warping Projector/Backprojector with a Distance Dependent Summing Kernel. 139. Song X, Frey EC, He X, Segars WP, Tsui BMW. Optimization of the Reconstruction and Post-Reconstruction Processing Parameters in Simultaneous Rest TI-201 and Stress Tc-99m Dual-Isotope Myocardial Perfusion SPECT. 140. Liu C, Tsui BMW, Baird WH, Wang Y, Frey EC. Evaluation of Rotating Slant Hole SPECT Mammography with Respect to Planar Scintimammography Using Monte Carlo Simulation Methods, Vol. 7, pp 4063-4067, 2004. 141. Veress AI, Segars WP, Tsui BMW, Weiss JA, Gullberg GT. Physiologically Realistic LV Models to Produce Normal and Infarcted Image and Phantom Data. *** The following 10 manuscripts are in: Conference Record of the 2005 IEEE Nuclear Science Symposium and Medical Imaging Conference, October 23-29, 2005, Puerto Rico 142. He X, Frey EC, Links JM, and Tsui BMW. Equivalence of percent correct on a 3-Class alternative forced choice task and volume under the 3-Class ROC surface. 143. Mok GSP, Wang Y, Tsui BMW. Design of a Novel Pinhole Collimator System for SPECT Imaging of Small Animals with Different Sizes. 144. Xu J, Liu C, and Tsui BMW, Investigation of imaging characteristics of rotating multi-segment slant-hole SPECT mammography using contrast-to-noise ratio criterion, pp. 1535–1538, 2005. 145. He X, Links JM, Tsui BMW and Frey EC. Three-class ROC analysis — decision theoretic approaches, Medical Decision Making Annual Conference, 2005 *** The following3 manuscripts are in: Conference Record of the 2006 IEEE SPIE Medical Imaging Conference, February 23-29, 2006, San Diego, CA 146. Fung GSK, Segars WP, Taguchi K, Fishman EK and Tsui BMW, "Development of a Computer Generated Model for the Coronary Arterial Tree Based on Multi-slice CT and Morphometric Data," Proc of SPIE MI, in press 2006. 147. Segars WP, Taguchi K, Fung GSK, Fishman EK and Tsui BMW, " Effect of Heart Rate on CT Angiography Using the Enhanced Cardiac Model of the 4D NCAT," Proc of SPIE MI, in press 2006. 148. Katsuyuki Taguchi, W. Paul Segars, George S. K. Fung, Benjamin W. M. Tsui, "Toward time resolved 4D cardiac CT imaging with patient dose reduction: estimating the global heart motion," Proc of SPIE MI, in press 2006. __________________________________________________________ + Graduate student under direct supervision * Postdoctoral Fellow/Research Associate under direct supervision
C. Book Chapters 1. Metz CE, Atkins FB, Tsui BMW, and Beck RN. Some New Insights into Collimator Design. (In) Radioactive Isotope in Klinik and Forschung, 13 (Verlag H. Egermann, 1978), pp. 783-795, 1978. 2. Austin JD, Tsui BMW, Strickland DC, Pizer SM, Staab EV, and Partain, CL. Three- Dimensional Display of NMR Images. (In) Technology of Nuclear Magnetic Resonance, Esser PD and Johnston RE, eds. (Society of Nuclear Medicine, NY), 1984, pp. 193-203. 3. Tsui BMW, Gunter DL, and Beck RN. Physics of Collimator Design. (In) Diagnostic Nuclear Medicine, Second Edition, Gottschalk A, Hoffer PB, Potchen EJ, Berger HJ, eds. (William and Wilkins, Baltimore), Chapter 6, Vol 1, pp. 42- 54, 1988. 4. Tsui BMW. Collimator Design, Properties and Characteristics. (In) SNM The Scintillation Camera, Simmons GH, ed. (Society of Nuclear Medicine), Chapter 2, pp. 17-45, 1988. 5. Tsui BMW. Fundamentals of SPECT. (In) Nuclear Medicine Update 1988, Yeh SDJ and Chan DCP, eds. (The Society of Nuclear Medicine, Republic of China, Taipei, Taiwan), pp. 27-42, 1988. 6. Tsui BMW and Zhao XD. Improvement of Cardiac SPECT Images with New Methods of Data Correction and Reconstruction. (In) Nuclear Medicine Update 1992, Chan DCP and D-Y Tzen, Eds. (Chinese American Society of Nuclear Medicine, Yi Hsien Publishing Co., Ltd., Taiwan, Republic of China), pp 105-112, 1992. 7. Tsui BMW. Reconstruction and Filtering Methods for Quantitative Cardiac SPECT Imaging. (In) Cardiovascular Nuclear Medicine and MRI: Quantitation and Clincal Applications, JHC Reiber and EE van der Wall eds., Kluwer Academic Publishers, Dordrecht, pp29-46, 1992. 8. Tsui BMW and Shung KK. Radionuclide Imaging. (In) Principles of Medical Imaging, Kirk Shung, Michael B. Smith and Benjamin Tsui, (Academic Press, CA), Chapter 3, pp 164-212, 1992. 9. Shih W-J, Biersack HJ and Tsui BMW. Nuclear Medicine: Single Photon Emission Computed Tomography. (In) Cerebrovascular Disease, Imaging and Interventional Treatment Options, CL Rumbaugh, A-M Wang and FY Tsai, eds., Igaku-Shoin, New York, pp 377-410, 1995. 10. Tsui BMW. SPECT (Single-Photon Emission Computed Tomography). (In) Biomedical Engineering Handbook, J. Bronzino, Ed., (CRC Press, Inc., Boca Raton, FL), pp1055-1076, 1995. 11. Jaszczak RJ and Tsui BMW. Chapter IV. Single Photon Emission Computed Tomography: General Principles. (In) Principles of Nuclear Medicine, 2nd Edition, Wagner H.N., Szabo Z. and Buchanan J.W. eds., (W.B. Saunders Company, Philadephia), pp 317-328, 1995. 12. Tsui BMW, Gunter DL, Beck RN and Patton JA. Physics of Collimator Design. (In) Diagnostic Nuclear Medicine, Third Edition, Sandler MP, Coleman RE, Wackers FJTh., Patton JA, Gottschalk A and Hoffer PB eds. (William and Wilkins, Baltimore), Chapter 6, Vol 1, pp. 67- 80, 1996. 13. Tsui BMW. Quantitative SPECT. (In) Nuclear Medicine. Henkin RE, Boles MA, Dillehay GL, Halama JR, Karesh SM, Wagner RH and Zimmer AM, (Mosby Year Book, Inc., St. Louis, MO), pp. 260-278, 1996. 14. Tsui BMW, Committe Member responsible for Chapter 5. Single Photon Emission Computed Tomography, (In) Mathematics and Physics of Emerging Biomedical Imaging, National Research Council, Institute of Medicine, (National Academy Press, Washington, D.C.), pp. 89-103, 1996. 15. Tsui BMW, Zhao XD, Frey EC and Gullberg GT. Characteristics of reconstructed point response in three-dimensional spatially variant detector response comepnstion in SPECT. (In) Three-Dimensional Image Recontruction in Radiology and Nuclear Medicine, Grangeat P and Amans J-L, Editors, (Kluwer Academic Publishers), pp 149-162, 1996. 16. Frey EC, Ju ZW and Tsui BMW. An investigation of two appoximation methods for improving the speed of 3D iterative reconstruction-based scatter compensation. (In) Three-Dimensional Image Recontruction in Radiology and Nuclear Medicine, Grangeat P and Amans J-L, Editors, (Kluwer Academic Publishers), pp 177-196, 1996. 17. Lalush DS and Tsui BMW. Space-time Gibbs priors applied to gated SPECT myocardial perfusion studies. (In) Three-Dimensional Image Recontruction in Radiology and Nuclear Medicine, Grangeat P and Amans J- L, Editors, (Kluwer Academic Publishers), pp 209-224, 1996. 18. Tsui BMW. Recent advances in SPECT. (In) Medical Physics, Second Mexican Symposium, Brandan M-E, Corral GH and Ortega-Martinez R, Editors, (American Institute of Physics), pp 97-106, 1998. 19. King MA, Tsui BMW, Pan T. Correction of Attenuation and Scatter for Single-Photon Emission Computed Tomography. (In) Nuclear Cardiology: State of the Art and Future Directions, 2d Edition, Barry L. Zaret and George A. Beller Editors, (Mosby), pp 125-136, 1999. 20. Faber TL, Galt JR, Chen Ji, Tsui BMW, Garcia EV. Detecting changes in myocardial perfusion. Computer Assisted Radiology and Surgery, HU Lemke, editor, in press, 2002. 21. Tsui BMW, Wang Y, Qi Y, Sawyer S, Frey EC, Majewski S, and Pomper MG. Feasibility of microSPECT/CT imaging of plaques in a transgenic mouse model. (In) Small Animal SPECT Imaging, Kupinski MA and Barrett HH, editors, (Springer), pp 215-224, 2005. 22. Segars WP, Wang Y and Tsui BMW. Effect of respiratory motion in plaque imaging in the mouse using Tc-99m labeled Annexin-V. (In) Small Animal SPECT Imaging, Kupinski MA and Barrett HH, editors, (Springer), pp 225-232, 2005. 23. Qi Y, Tsui BMW, Wang Y, Yoder B, Wojcik R, Majewski S and Weisenberger AG. Development and characterization of a high-resolution microSPECT system for small animal imaging. (In) Small Animal SPECT Imaging, Kupinski MA and Barrett HH, editors, (Springer), pp 259-266, 2005. 24. Frey EC and Tsui BMW. Correction for Collimator Response Function in SPECT. (In) Quantitative Analysis of Nuclear Medicine Images. Zaidi H, Editor, Kluwer Academic/Plenum Publishers, pp141-166, 2005. 25. Tsui BMW and Frey EC. Analytic Image Reconstruction Methods. (In) Quantitative Analysis of Nuclear Medicine Images. Zaidi H, Editor, Kluwer Academic/Plenum Publishers, pp 82-106, 2005. D. Other Media (Audio/Visual Programs)1. Tsui BMW. Collimator Design, Properties and Characteristics. Continuing Education Lectures, SNM 34th Annual Meeting Programs, Society of Nuclear Medicine, CEL 108, 1987. 2. Tsui BMW. Basic Principles of SPECT Imaging. Continuing Education Lecturers, SNM 34th Annual Meeting Programs, Society of Nuclear Medicine, CEL 99, 1987. 3. Tsui BMW. Physics of SPECT. In Cross-sectional Imaging: Emission Tomography, AAPM/RSNA 1994 Physics Tutorial for Residents, AAPM and RSNA, 1994. E. Others Publications1. Tsui BMW. Application of Iterative Reconstruction Methods in SPECT. Computer and Instrumentation Council Newsletter, The Society of Nuclear Medicine, Vol 8, No. 2, 1990. 2. Frey EC* and Tsui BMW. Evaluation of Workstations for SPECT Reconstruction. Computer and Instrumentation Council Newsletter, The Society of Nuclear Medicine, Vol 9, No. 1, 1991. 3. Koral KF, Buchbinder S, Clinthorne NH, Rogers WL, Swailem FM and Tsui BMW. Influence of region of interest selection on the scatter multiplier required for quantification in dual-window Compton correction. Letter to the Editor, J Nucl Med 32:186-187, 1991.
Extramural Sponsorship
A. Current (Principal Investigator) 1. NIH research grant, Corrective Image Reconstruction Methods for ECT, 9 R01 EB 000168, Benjamin M.W. Tsui, Principal Investigator, 4/1/02-3/31/07, 30% effort, $1,788,574 total direct costs. 2. U.S. Army CDMRP Idea Development Award, Corrective In-111 Capromab Pendetide SPECT Image Reconstruction Methods for Improved Detection of Recurrent Prostate Cancer, Benjamin M.W. Tsui, Ph.D., Principal Investigator, 5/19/03-5/18/06, 5% effort, $367,486 total direct costs 3. NIH research grant, Task-Based Optimization for Gated Myocardial SPECT, 1R01HL68075, Benjamin M.W. Tsui, Ph.D., Principal Investigator, 8/1/01-7/31/05, 10% effort, $425,000 total direct costs 4. NIH research grant, Improved Heart SPECT Imaging with Convergent Collimators, 9 R01 EB 000121-14 Benjamin M.W. Tsui, Ph.D, Principal Investigator of Johns Hopkins University subcontract, 3% effort, 4/1/02-3/31/06, total direct costs $499,820. 5. NIH research grant, Simultaneous Dual Isotope SPECT w/Cross-talk Correction, 8 R01 EB 00288-04, Eric C. Frey, Ph.D., Principal Investigator, 5% effort, 2/1/03-1/31/08, total direct cost $1,125,000. 6. NIH research grant, Comprehensive Validation of Cardiac SPECT Reconstruction, 1 R01 HL68575-01, Jonathan Links, Ph.D. Principal Investigator, 6% effort, 1/01/02-12/31/05, total direct costs $385,592 7. NIH research grant, Mammo & Cardiac SPECT w/Rotating Slant Hole Collimator, R01 EB 001983, Benjamin M. Tsui, Ph.D., Principal Investigator, 15% effort, 8/1/03-7/31/07, total direct cost $1,000,000. 8. NIH research grant, Interdisciplinary Small Animal Imaging for Oncology, R24 CA92871, Martin Pomper, M.D., Ph.D., Principal Investigator, 5% effort, 7/1/01-6/30/06, annual direct costs $3,403,670. 9. NIH research grant, High Resolution SPECT for Molecular Imaging, 1 R01 EB 001558, Benjamin M.W. Tsui, Ph.D., Principal Investigator, 10% effort, 9/1/04-8/31/08, total direct costs, $397,042. 10. NIH research grant, Simulation Tools for Dynamic CT, R01 EB 001838, W. Paul Segars, Principal Investigator, 10% effort, 4/1/05-3/31/10, total direct costs, $1,250,000. 11. NIH research grant, Quantitative SPECT for Targeted Radionuclide Therapy, R01 CA 109234, Eric C. Frey, Ph.D., Principal Investigator, 5% effort, 4/1/05-3/31/10, total direct costs, $1,614,605. 12. DOE research grant, Patient Specific Dosimetry and Radiobiological Modeling of Targeted Radionuclide Dosimetry, George Sgouros, Ph.D, Principal Investigator, 5% effort, total costs $1,149,017, 1/1/05-12/31/07. 13. GE Healthcare Technology Research Contract, Applications of In-111 SPECT Using GE Nuclear Medicine Systems, Benjamin M.W. Tsui, Ph.D., Principal Investigator, 3% effort, 6/1/04-5/31/07, total costs, $150,000.
B. Pending (Principal Investigator) 1. Siemens Medical Systems Research Contract, CT Imaging Research, Benjamin M.W. Tsui, Ph.D., Principal Investigator, 3% effort, 3/1/06-2//28/07, total costs, $150,000.
C. Previous 1. Research Contract, US Army Ballistics Research Laboratory, Design of an Electronic X-ray Detector System for the BRL Microsecond Computer Tomography Facility, Co-PI, 5/20/84-11/20/84, total direct costs $69,793 2. NIH program project grant, "Medical Image Presentation", 1PO1CA47982, Stephen M. Pizer, Ph.D., Program Director, PI of Project 3, Multimodality 3D Display in SPECT, 7/01/88-6/30/91, total direct costs of Project 3 $345,241 3. NIH research grant, Evaluation of Corrective Image Reconstruction Methods in SPECT, 1RO1CA39463, Benjamin M. Tsui, Ph.D., PI, 12/01/86-11/30/89, total direct costs $402,501 4. NIH research grant, Improved Heart Imaging Using SPECT with Convergent Hole Collimators, RO1HL39792, Benjamin M. Tsui, Ph.D., PI of UNC subcontract, 7/1/88-6/30/91, total direct costs of subcontract $159,451 5. NIH research grant, Evaluation of Corrective Image Reconstruction Methods in SPECT, 2RO1CA39463, Benjamin M. Tsui, Ph.D., PI, 40% effort, 12/01/89-7/31/95, total direct costs $1,160,300 6. NIH research grant, Improved Heart Imaging Using SPECT with Convergent Hole Collimators, RO1HL39792, Benjamin M. Tsui, Ph.D., PI of UNC subcontract, 10% effort, 7/1/91-6/30/94, total direct costs of subcontract $214,872 7. NIH research grant, "Development of an Emission-Transmission CT System", BH Hasegawa, Ph.D., UCSF, Principal Investigator of entire project, Benjamin M. Tsui, Ph.D., Ph.D., Principal Investigator of UNC-CH subcontract, 5% effort, 7/1/92-6/30/96, total direct cost of subcontract $111,538 8. NIH research grant, Evaluation of Corrective Image Reconstruction Methods in SPECT, 3RO1CA39463, Benjamin M. Tsui, Ph.D., Principal Investigator, 40% effort, 8/01/95-7/31/98, total direct costs $690,975 9. NIH research grant, Improved Heart Imaging Using SPECT with Convergent Hole Collimators, RO1HL39792, Benjamin M. Tsui, Ph.D., Principal Investigator of UNC subcontract, 10% effort, 7/1/94-6/30/99, total direct costs of subcontract $406,511 10. NIH research grant, Improved Scintimammography for Breast Cancer Diagnosis, Benjamin M. W. Tsui, Ph.D., Principal Investigator, 5% effort, 4/01/97-3/31/02, total direct cost $799,707 11. NIH research grant, Improved Heart Imaging Using SPECT with Convergent Hole Collimators, RO1HL39792, U. of Utah, Grant T. Gullberg, Ph.D. Principal Investigator of the entire project. Benjamin M. W. Tsui, Ph.D. Principal Investigator of UNC subcontract, 10% effort, 4/1/99-3/31/02, total direct cost $250,829 12. NIH research grant, Evaluation of Corrective Image Reconstruction Methods in ECT, 4RO1CA39463, Principal Investigator, 17% effort, 8/01/98-3/31/02, total direct costs $936,290. 13. Research Contract, Siemens Medical Systems, Nuclear Medicine, Benjamin M. W. Tsui, Ph.D., Principal Investigator, 3% effort, 11/1/98-6/30/02, total direct cost $240,000 14. Whitaker Foundation Special Opportunity Award, Biomedical Engineering for Functional Genomics, Benjamin M. Tsui, Ph.D., Principal Investigator, 10% effort, 8/1/01-7/31/04, total direct cost $1,395,618. . EDUCATIONAL ACTIVITIES A. Classroom Instruction at Johns Hopkins University
B. Classroom Instruction at the University of North Carolina at Chapel Hill, Chapel Hill, NC
Mentoring (pre and postdoctoral) A. Current Graduate Student Advisees
B. Previous Graduate Student Advisees
C. Current Postdoctoral and Research Associates
D. Previous Postdoctoral Research Fellows and Research Associate Advisees 1. Eric C. Frey, Ph.D., Research Associate, 1989-1991; Posdoctoral Research Fellow, 1988-1989, UNC-CH 2. Zong Jian Cao, Ph.D., Postdoctoral Research Fellow, 1990-1991, Research Associate, 1991-1993, Research Assistant Professor, 1993-1994, Department of Biomedical Engineering, University of North Carolina at Chapel Hill
E. Thesis Committees 1. Current Ph.D. Dissertation, Principal Advisor
2. Current Ph.D. Dissertation, Committee Member
3. Current M.S. Thesis, Principal Advisor
4. Current M.S. Thesis, Committee Member
5. Completed Ph.D. Dissertations, Principal Advisor
6. Completed Ph.D. Dissertations, Committee Member
7. Completed M.S., Principal Advisor
8. Completed M.S., Committee Member
International Atomic Energy Agency Fellowship Training grant, Recent procedures of SPECT and PET for the assessment of myocardial viability and evaluation of perfusion and functional parameters. Trainee, Dr. Yueqin Tian, China, 1/1/03 – 6/30/03.
B. Member, Main Editorial Board, Physics in Medicine & Biology, 1996-2002 C. Member, Editorial Board, Journal of Nuclear Cardiology, 2000-present D. Deputy Editor-in-Chief, Annals of Nuclear Medicine and Sciences, The Society of Nuclear Medicine, Republic of China, 1999-present E. Member, Advisory Editorial Board, Annals of Nuclear Medicine and Sciences, The Society of Nuclear Medicine, Republic of China, 1995-1999 F. Associate Conference Editor, IEEE Nuclear Science Symposium and Medical Imaging Conference, 1994-1996 G. Guest Editor, IEEE Nuclear Science Symposium and Medical Imaging Conference, 1993-1994 H. Reviewer, IEEE Transactions in Medical Imaging, IEEE Transactions in Nuclear Science, Journal of Nuclear Medicine, Medical Physics, Physics in Medicine and Biology, Jounral of Nuclear Cardiology, Investigative Radiology, Radiology, Journal of Optical Society of America, Science ORGANIZATIONAL ACTIVITIES Institutional Administration AppointmentsA. University Committee Memberships Member, Users Group, Office of Licensing and Technology Development, Johns Hopkins University, 2005-present Member, Advisory Committee for the development of a joint UNC-Chapel Hill-NC State University Department of Biomedical Engineering, 2001-2002 B. School of Medicine Committee Memberships Member, Post-Tenure Review Committee, School of Medicine, UNC-CH, 2001-2002 Member, Research Advisory Committee (RAC), School of Medicine, UNC-CH, 2001-2002 Member, Dean’s Advisory Committee, School of Medicine, UNC-CH, 2001-2002 C. Departmental Committee MembershipsMember, Promotions Committee, The Russell H. Morgan Department of Radiology, Johns Hopkins University, 2004-present Member, Executive Committee, The Russell H. Morgan Department of Radiology, Johns Hopkins University, 2002-present Chair, Radiology Office of Research Administration and Training Review Committee. The Russell H. Morgan Department of Radiology, Johns Hopkins University, 2002-present Member, Advisory Committee, Department of BME, UNC-CH, 1992-2002 Member, Appointment and Promotion Committee, Department of BME, UNC-CH, 1992-2002 Member, Full Professor Committee, Department of BME, UNC-CH, 1992-2002 Member, Full Professor Committee, Department of Radiology, UNC-CH, 1992-2002 Member, Computer Committee, Department of BME, UNC-CH, 1990-1999
Professional Societies A. Administrative Appointments President, Chinese American Society of Nuclear Medicine, 1995-1997 President-Elect, Chinese American Society of Nuclear Medicine, 1993-1994 Treasurer, Southeastern Chapter of the Society of Nuclear Medicine, 1997-1999 Member, Society of Nuclear Medicine's Computer and Instrumentation Council 1991 Focus Group on Quantitative Imaging, 1991- 1994 Member, Executive Committee, Computer and Instrumentation Council, Society of Nuclear Medicine (SNM), 1991-1993 Member, Board of Directors, Brain Imaging Council, Society of Nuclear Medicine (SNM), 1988-1992 B. Membership Fellow, Institute of Electrical and Electronic Engineers (IEEE), 2005-present Fellow and Chartered Physicist, Institute of Physics (IOP), 1999-present Fellow, American Institute for Medical and Biological Engineers (AIMBE), 1997-present Member, Basic and Translational Sciences Committee, Academy of Radiology Research, 2002-present Member, International Commission on Radiation Units and Measurements (ICRU) Report Committee on Assessment of Image Quality in Nuclear Medicine, 2001-present Senior Member, Institute of Electrical and Electronic Engineers (IEEE), 1985-2004 Member, Academy of Molecular Imaging (AMI), 2002-present Member, Society of Nuclear Medicine (SNM), 1978-present Member, American Association of Physicists in Medicine (AAPM), 1976-present Member, Biomedical Engineering Society (BMES), 1990-present Member, Society of Magnetic Resonance in Medicine (SMRM), 1985-present Member, American Society of Nuclear Cardiology (ASNC), 1995-present Member, Instrumentation and Computer Council, Society of Nuclear Medicine (SNM), 1989-present Member, Southeastern Chapter, Society of Nuclear Medicine (SNM), 1991-present Member, Chinese American Society of Nuclear Medicine, 1985-present Member, Association of University Radiologists (AUR), 1980-1992 Conference Organizer General Chairr, IEEE Nuclear Science Symposium and Medical Imaging Conference, Honolulu, HI, October 16-23, 2007. Member, Program Committee, 2002 IEEE International Symposium on Biomedical Imaging: Macro to Nano, Washington, D.C., 7 - 10 July 2002. Program Chairman, Medical Imaging Conference, IEEE Nuclear Science Symposium and Medical Imaging Conference, San Diego, CA, November 3-10, 2001. Sub-Chair, Program Committee, Annual Meeting of the Society of Nuclear Medicine, 2000-2002 Member, Program Committee, Medical Imaging Conference, IEEE Nuclear Science Symposium, 1991-2000. Member, Program Committee, International Meeting on Fully Three-dimensional Image Reconstruction for Radiology and Nuclear Medicine, 1995-2001 Co-Chair, Imaging and Imaging Processing Track, 1999 Joint BMES-EMBS Conference, Atlanta, GA, Oct 13-16, 1999. Chair, Cardiovascular Imaging Track, 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Hong Kong, 1998 Sub-chairman, Scientific Program Committee, 40th Annual Society of Nuclear Medicine, Toronto, Canada, June 10-13, 1993 Member, Scientific Program Committee, Annual Society of Nuclear Medicine Meeting, 1992, 1994-1995, 1998 Member, Program Committee, 1991 Southeastern Chapter of the Society of Nuclear Medicine Meeting, Hollywood, Florida, October 11-13, 1991 Member, Program Committee, Technology for Health, 1991 Annual Fall Meeting of the Biomedical Engineering Society, Charlottesville, Virginia, October 12-14, 1991. Moderator, SPECT Image Reconstruction Techniques, Continuing Education Course, in Society of Nuclear Medicine 35th Annual Meeting, San Francisco, California, June 14-17, 1988 Chair, Medical Engineering - Medical Imaging of the Brain, in Second SCBA (Society of Chinese Bioscientists in America) International Symposium and Workshop, Univ. of California, Berkeley, California, June 27-30, 1988
Advisory Committees, Review
Groups A. NIH Workshops Invited Participant, NIBIB Bioengineering and Biomedical Imaging Training Workshop, Bethesda, MD, August 26-27, 2002. Invited Participant, NIBIB Workshop on Defining the State-of-the-Art in Biomedical Imaging: Research Needs for the Future, Jackson, MS, March 16-18, 2003. B. Scientific Grant Review Committees: NIH Study Sections Member, NIH Study Section, Special Emphasis Panel for RFA-CA-05—24: Centers of Cancer Nanotechnology Excellence, Washington, DC, July 19-22, 2005 Member, NIH Study Section, ZRG1 SBIB-D 02M: Bioengineering Imaging and Imaging Technology, Washington, DC, July 7, 2005 Member, NIH Study Section, ZRG1 SBIB-L 91S: Cone-Beam CT, Washington, DC, April 5, 2005 Member, NIH Study Section, ZRG1 SBIB-J 50R: PAR-04-023: Bioengineering Research Partnerships, San Diego, CA, February 11, 2005 Member, NIH Study Section, ZRG1 SBIB-J (90) (S), Special Emphasis Panel/Initial Review Group, Tyson Corner, VA, November 15-16, 2004. Member, NIH Study Section, ZRG1-SRB (50) Bioengineering Partnership grant applications, LaJolla, CA, February 12, 2003 Member, NIH Study Section, SSS-9, SSS-9(35), SSS-9(40), SSS-9(41) SSS-9(10) and SSS-9(11) grant applications, March 6-8, 2002 Member, NIH Study Section, Development of Novel Technologies for In Vivo Imaging, October 1-2, 2001 Member, NIH Diagnostic Imaging Study Section, Surgery, Radiology and Bioengineering Initial Review Group, October 17-19, 1999 Member, Special Emphasis Panel for NIH RFA AI-99-005: “Immunological Phenotyping of Mouse Mutants”, August 5, 1999 Member, NIH Multidisciplinary Sciences Special Emphasis Panel, ZRG7 DMG (1), June 1997 Member, NIH NCI Special Review Committee for R13 CA73729, January, 1996 Member, NIH Study Section on Diagnostic Radiology, February 8-9, 1996 Member, NIH Special Study Section - 9, March 20-22, 1994 Chairperson, NIH Multidisciplinary Special Emphasis Panel, ZRG7 SSS-X, December 15, 1993 Member, NIH Special Study Section - 9, June 30 - July 2, 1993 Member, NIH reverse site visit team for Washington University Resource Grant application, February, 1993 Member, Diagnostic Radiology Study Section, Division of Research Grants, National Institute of Health (NIH), 1988-1992 Member, NIH site visit team for University of Arizona program project grant application, May, 1991 Member, NIH reverse site visit team for University of Michigan program project grant application, April, 1991 Member, NIH Ad Hoc SRC Review Committee for RFA 90-CA-21 applications, NIH, April, 1991 Member, NIH site visit team for University of Arizona program project grant application, March, 1990 Member, NIH site visit team for University of Michigan program project grant application, July, 1990 Reviewer, NIH NCI Outstanding Investigator Grant (OIG) application, October 1989 Member, NIH Special Study Section on Diagnostic and Therapeutic Radiology, NIH, December, 1987 Member, NIH Special Study Section on Ultrasound and Magnetic Resonance Imaging, NIH, April, 1987 Member, NIH site visit team for University of Southern California program project grant application, March, 1987 C. Scientific Grant Review Committees: Other US Government Grant Funding Agencies Member, Scientific Review Committee BC-RON, 2001 Breast Cancer Research Program (BCRP), Department of Defense Congressionally Directed Medical Research Programs (CDMRP), August 15-17, 2001 Member, Review Panel, National Science Foundation (NSF) Faculty Early Career Development (CAREER) Program, January 9-10, 2001 Member, Scientific Review Committee BC-RON, 2000 Breast Cancer Research Program (BCRP), Department of Defense Congressionally Directed Medical Research Programs (CDMRP), August 16-18, 2000 Member, 1998 Breast Cancer Research Program (BCRP), Department of Defense United States Army Medical Research and Material Command (USAMRMC), September 18-20, 1998 Member, 1997 Breast Cancer Research Program (BCRP), Department of Defense United States Army Medical Research and Material Command (USAMRMC), September 5-7, 1997 Member, review panel for assessment of projects in the Nuclear Medicine Program of the Department of Energy Office of Health and Environmental Research, April 1992 Reviewer, grant application, Physical and Technological Research Division, Office of Health and Environmental Research, Department of Energy, July, 1988 D. Scientific Grant Review Committees: US State Government Grant Funding Agencies Member, Study Section, Technologies for Earlier Detection, Breast Cancer Research Program, University of California for the State of California, March 27, 1998 Member, Study Section, Technologies for Earlier Detection, Breast Cancer Research Program, University of California for the State of California, March 31 - April 1, 1996 Member, Study Section, Technologies for Earlier Detection, Breast Cancer Research Program, University of California for the State of Califorina, May 22-23, 1995 E. Scientific Grant Review Committees: Private Foundation Grant Funding Agencies Guest Member, Scientific Advisory Committee, Whitaker Foundation, April 24-25, 1994 F. Scientific Grant Review Committees: Foreign Government Grant Funding Agencies Member, National Health Research Institutes Grant Review Committee, August 12-14, 2003, Taipei, Taiwan, ROC Member, National Health Research Institutes Grant Review Committee, September 5-7, 2002, Taipei, Taiwan, ROC Member, National Health Research Institutes Grant Review Committee, September 4-6, 2001, Taipei, Taiwan, ROC Member, Medical Biotechnology Committee, National Health Research Institutes, Department of Health, The Republic of China, 1994-1998 Reviewer, grant application, British Columbia Health Care Research Foundation, Canada, 1989, 1994. G. National Committees Member, Committee for "Emerging Dynamic Biomedical Imaging", National Academy of Science (NAS) and the Institute of Medicine (IOM) of the National Research Council (NRC), 1993-1995 H. International/Foreign Committees Member, Advisory Committee, Positron Emission Tomography (PET) Imaging Center, Tri-Service General Hospital, Taipei, Taiwan, June 2001 to December 2001 Invited participant, National Development Seminar, The Republic of China, July 17-22, 1995 I. Advisory Boards Member, Medical Advisory Board, Nuclear Business, General Electric Medical Systems, 1992-1993 RECOGNITION Fellow, Institutes of Electrical and Electronics Engineers (IEEE), 2005- Fellow and Chartered Physicist, Institute of Physics (IOP), 1999- Fellow, American Institute for Medical and Biological Engineering (AIMBE), 1997- Kodak Scientific Research Award - 1977 University of Chicago Fellowship - 1973-1977 Dartmouth College Fellowship - 1970-1972 Hong Kong Government Fellowship - 1966-1970 Scholastic Achievement Award - 1965-1966
External Examiner of Ph.D. Dissertation, “Scatter amd Attenuation Correction Techniques for Absolute Quantification of Radionuclide distributions with SPECT” by Hanlie Naude, The University of The Orange Free State, South Africa, July, 1998 External Examiner of Ph.D. Dissertation, “Attenuation Correction in Cone-Beam Geometry Using Transmission Scans in SPECT” by Valerie La, Institut National Polytechnique de Grenoble, Grenoble, France, September 23, 1997 External Examiner of Ph.D. Dissertation, "Analytical Calculations of Photon Distributions in SPECT Projections" by Roger Glenn Wells, Department of Physics and Astronomy, University of British Columbia, Vancouver, Canada, August 25, 1997 External Examiner of Ph.D. Dissertation, “Fusion of Anatomical and Functional Medical Images” by Babak Assai Ardekani, University of Technology, Sydney, Australia, 1995
William Mong Distinguished Visiting Professor, University of Hong Kong, September 20-24, 2004. Visiting Professor, Institute of Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, March 7-14, 2003. Visiting Professor, Tri-Service Hospital, Taipei, Taiwan, December 2-6, 2002 Visiting Professor, Yang Ming National University, Taipei, Taiwan, March 10-14, 2002. Invited Lecturer, VIII Argentina Congress of Medical Physics, Mendoza, Argentina, November 25-28, 1999. Distinguished Visiting Scientist, sponsored by the Medical Research Council, South Africa, hosted by the Department of Medical Physics, The Orange Free State University, Bloemfentein, South Africa, May 11-30, 1999. Invited Course Lecturer, Commission Training in Nuclear Medicine Imaging, sponsored by the Hospital Authority, Hong Kong, November 23-28, 1998.
Invited Lectures at Scientific Meetings1. The Problem of Collimator Selection Based on Theoretical Models and Observer Performance. Speaker in the World Federation of Nuclear Medicine and Biology, Second International Congress, Washington, DC, 1978. 2. Magnetic Resonance Imaging. Speaker at the IEEE Eastern North Carolina Section's Meeting, North Carolina State University, Raleigh, NC, September 9, 1987. 3. Collimation in SPECT Imaging of the Brain. Speaker in the Symposium on Brain Imaging sponsored by General Electric Company and Medi-Physics, Orlando, Florida, September 15, 1987. 4. Recent Advances in SPECT Instrumentation and Image Processing Techniques. Lecture at the Society of Nuclear Medicine Southeastern Chapter Meeting, Orlando, Florida, September 16-17, 1987. 5. Current Status of SPECT Imaging Instrumentation and Techniques. Speaker in UNC Radiology Symposium, Hilton Head, South Carolina, April 1987. 6. Magnetic Resonance Imaging. Speaker in UNC Radiology Symposium, Hilton Head, South Carolina, April 1987. 7. The Fundamentals of SPECT. Speaker at the Teaching Lesson of the 4th Asian and Oceania Congress of Nuclear Medicine. Taipei, Taiwan, Republic of China, November 1-4, 1988. 8. Recent Advances in SPECT Image Reconstruction and 3D Display. Invited speaker at the Scientific Meeting of NorthEastern Chapter of the American Association of Physicists in Medicine (AAPM), Worcester, Massachusetts, February 15, 1989. 9. Recent Advances Image Processing and 3D Display in SPECT. Invited Lecturer at The High Country Nuclear Medicine Conference, Vail, Colorado, March 13-17, 1989. 10. Recent advances in SPECT instrumentation, image processing and clinical applications. Invited lecture at the 20th Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine, Christchurch, New Zealand, August 21-23, 1989. 11. Recent advances in SPECT instrumentation, image processing and clinical applications. Invited lecture at the Australian Chapter of the Australian and New Zealand Society of Nuclear Medicine, Sydney, Australia, August 24, 1989. 12. Iterative Reconstruction Methods for Quantitative SPECT. Invited speaker at the Society of Nuclear Medicine's "New Horizons in SPECT in SPECT, PET and Computers" Symposium at the 1991 Mid-Winter Meeting, Tampa, Florida, February 4-5, 1991. 13. Reconstruction and Filtering Methods for Quantitative Cardiac SPECT Imaging. Invited speaker at the 2nd International Symposium on Computer Applications in Nuclear Medicine and Cardiac Magnetic Resonance Imaging, Rotterdam, March 20-22, 1991. 14. Recent Advances in Emission Computed Tomography. Invited speaker at the 1991 Annual Fall Meeting of the Biomedical Engineering Society, Charlottesville, VA, October 12-14, 1991. 15. Three-Dimensional Display of SPECT images. Invited speaker at the 4th Mid-Atlantic AVS Users Group Meeting, Washington, D.C., January 15, 1992. 16. Clinical Role of Quantitative SPECT. Invited speaker at the Society of Nuclear Medicine Computer & Instrumentation Syposium, Nuclear Medicine Computers and Instrumentation: Towards the 21st Century, Dallas/Fort Worth, TX, February 10-11, 1992. 17. Applying Iterative Algorithms to SPECT Reconstruction: Issues of Properties and Compensation. Invited speaker, "2nd Midwest Workshop on Iterative Image Reconstruction", The University of Minnesota, Minneapolis, September 11&12, 1992. 18. Recent Advances in SPECT. Invited speaker at "the Physics of Medical Imaging, PET, SPECT X-ray" sponsored by the UCLA Department of Physics & the Center for Advanced Accelerators, Los Angeles, CA, January 20, 1993. 19. Quantitative SPECT Reconstruction Methods: Current Research and Clinical Applications. Invited speaker, New England Chapter of the AAPM meeting, Roxbury V.A. Medical Center, West Roxbury, Massachusetts, February 23, 1993. 20. Recent Advances in SPECT Instrumentation and Reconstruction Methods. World Chinese Conference of Nuclear Medicine, Wuxi, China, August 8-11, 1993. 21. Recent Advances in SPECT Instrumentation and Reconstruction Methods. Invited Speaker, The 1st Medical Engineering Week of the World, The 3rd International Symposium-Biomedical Engineering in the 21st Century & The 1st IEEE/EMBS Region 10 International Conference & Clinical Engineering Symposium, Taipei, Taiwan, ROC, September 25-29, 1994. 22. Emission Computed Tomography. Invited Speaker, The 1st Medical Engineering Week of the World, The 3rd International Symposium-Biomedical Engineering in the 21st Century & The 1st IEEE/EMBS Region 10 International Conference & Clinical Engineering Symposium, Taipei, Taiwan, ROC, September 25-29, 1994. 23. Attenuation Correction for Cardiac SPECT. Invited Speaker, Nuclear Cardiology Symposium and Workshop, Milwaukee, WI, October 19-21, 1994. 24. SPECT Imaging. Invited Speaker, The First IEEE International Conference on Image Processing, Austin, Texas, November 13-16, 1994. 25. Comparison of Reconstruction Algorithms. Invited Speaker, State-of-the-Art Reviews, the 6th World Congress of the World Federation of Nuclear Medicine & Biology, Sydney, Australia, October 23-28, 1994. 26. Quantitative SPECT Reconstruction Methods. Invited Speaker, Session on “Medical Imaging”, 1995 Annual Fall Meeting of the Biomedical Engineering Society, Boston, October 6-8, 1995. 27. Attenuation and Scatter Compensation Methods in Cardiac SPECT. Invited Speaker, Cardiovascular Science & Technology Conference in the 42nd Annual Conference of the American Society for Artificial Internal Organs, Washington, D.C., May 2-4, 1996. 28. Attenuation and Scatter Compensation Methods for Improved Myocardial SPECT. Invited Speaker, The 2nd Medical Engineering Week of the World, Taipei, Taiwan, ROC, May 27-30, 1996. 29. Instrumentation and Imaging Configuration Considerations for Scintimammography. Invited Speaker, The 2nd Medical Engineering Week of the World, Taipei, Taiwan, ROC, May 27-30, 1996. 30. Attenuation and scatter corrections: Update and pitfalls. Invited Speaker, The 37th Annual Meeting of the Southeastern Chapter of the Society of Nuclear Medicine, Atlanta, GA, October 18-20, 1996. 31.The Role of Simulation Techniques in the Future of Nuclear Medicine. Invited Lecture at the Symposium on Future Directions in Nuclear Medicine Physics and Engineering, University of Chicago, Chicago, IL, March 19-21, 1999. 32.Attenuation Correction: Scatter Correction and Interative Reconstruction. Invited Lecture in the Session on Technical Advances in SPECT Systems at the 4th International Conference of Nuclear Cardiology, Athens, Greece, April 18-21, 1999. 33.Renaissance Perspectives in Nuclear Cardiology. July 11-18, 1999, Siena, Italy. 34.Iterative Reconstruction Algorithms. Invited Lecture in the VIII Argentina Congress on Medical Physics, Mendoza, Argentina, November 25-28, 1999 35.Collimators for SPECT. Invited Lecture in the VIII Argentina Congress on Medical Physics, Mendoza, Argentina, November 25-28, 1999. 36.Correction of Attenuation and Scatter in SPECT. Invited Lecture in the VIII Argentina Congress on Medical Physics, Mendoza, Argentina, November 25-28, 1999. 37.Attenuation and scatter correction. Invited Lectur, Nuclear Cardiology Today – 2000 and Beyond. May 25-27, 2000, Cesena, Italy. 38. Computer Generated Phantoms. Invited speaker, Integrated Research Team Meeting of the Telemedicine and Advanced Technology Research Center (TATRC), U.S. Army Medical Research and Material Command (USAMRMC), September 20-22, 2000, Frederick, MD. 39. Rotating Slant Hole SPECT Mammography. Invited speaker, Functional Breast Imaging with Advanced Detectors, April 18-21, 2001, Rome, Italy. 40. Attenuation Correction. Invited Lecture in the Session on Advances in Nuclear Cardiology: Advances in Nuclear Instrumentation at the 5th International Conference of Nuclear Cardiology, Vienna, Austria, May 2-5, 2001. 41. Corrections: Attenuation, Resolution Recovery, Scatter. Invited Lecture for the 8th Congress of the World Federation of Nuclear Medicine and Biology, Santiago, Chile, September 29-October 4, 2002. 42. Simulation Studies, Invited presentation at the 8th Congress of the World Federation of Nuclear Medicine and Biology September 27 -October 4, 2002 43. Image Degrading Factors and their Compensation in Myocardial SPECT, Invited presentation at the International Symposium on Cardiovascular Nuclear Medicine, Beijing, China, May 27-31, 2002. 44. Micro-SPECT, Invited presentation at the International Symposium on Biomedical Imaging, Washington, D.C., July 7-9, 2002. 45. Micro-SPECT, Invited presentation at the 6th Nuclear Cardiology Invitational Conference, Reno/Tahoe, NV, July 21-24, 2002. 46. Research Needs for Data/Image Reconstruction, Invited presentation at the NIBIB/MMC Workshop on Defining the State-of-the-Art in Biomedical Imaging: Research Needs for the Future, University of Mississippi Medical Center, Jackson, MS, March 16-18, 2003 47. Pinhole Single and Multi-Detector SPECT, Invited presentation at the 6th International Conference in Nuclear Cardiology, Florence, Italy, April 26 - May 1, 2003 48. Small Animal SPECT Development, Invited presentation at the Molecular Imaging Symposium, London, Ontario, Canada, July 20-21, 2003. 49. Iterative Image Reconstruction in Nuclear Medicine, Invited presentation at the 14th ACRT (Asian Conference of Radiographers and Radiological Meeting, Bangkok, Thailand, August 19-22, 2003 50. PET Systems and Best Buy, Invited presentation at the 14th ACRT (Asian Conference of Radiographers and Radiological Meeting, Bangkok, Thailand, August 19-22, 2003 51. Implementation and Applications of Quantitative SPECT, Invited presentation at the World Congress on Medical Physics and Biomedical Engineering, Sydney, Australia, August 24-29, 2003 52. Image Reconstruction and Filtering, Invited presentation at the 8th Annual Symposium and Scientific Session of the Society of Nuclear Cardiology (ASNC), Indianapolis, IN, September 10 - 13, 2003. 53. Quantitative SPECT Imaging of Prostate Cancer, Invited presentation at the Topical Symposium on Advanced molecular imaging techniques in the detection, diagnosism therapy and follow-up of prostate cancer, Rome, Italy, December 6-7, 2005. Invited Lectures at Continued Education Courses1. Basic Principles of SPECT Imaging. Lecture in Continued Education Course, Soc of Nuclear Medicine 34th Annual Meeting, Toronto, Canada, June 1987. 2. Collimator Design, Properties and Characteristics. Lecture in Continued Education Course, Society of Nuclear Medicine 34th Annual Meeting, Toronto, Canada, June 1987. 3. Basic Principles of SPECT Imaging. Lecturer at the Eastern Carolina Continuing Education Center, New Bern, NC, Nov 18, 1987. 4. Image Reconstruction Techniques (with special reference to SPECT). Invited lecture at summer course on “Modern Applications of Nuclear Medicine”, Department of Hospital Physics, Karolinska Hospital, Stockholm, Sweden, August 16, 1994. 5. Physics of SPECT. In “Cross-Sectional Imaging: Emission Tomography”, Physics Tutorial for Residents, the 80th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Chicago, IL, November 27- December 2, 1994. 6. Recent Developments in SPECT. In “Clinical Relevant Developments in Planar, SPECT and PET Imaging Devices”, Continuing Education Lectures, Society of Nuclear Medicine’s 42 Annual Meeting, Minneapolis, Minnesota, June 11-15, 1995. 7. Attenuation and Scatter Compensation in Cardiac SPECT, The High Country Nuclear Medicine Conference, The Education & Research Foundation of The Society of Nuclear Medicine, Vail, Colorado, March 8-13, 1996. 8. Emerging Attenuation, Scatter and Detector Response Compensation Methods, in “SPECT -- Principles, Instrumentation and Major Factors Affecting Clinical Image Quality”, Categorical Seminar at the Society of Nuclear Medicine’s 43 Annual Meeting, Denver, Colorado, June 1-6, 1996. 9. Basics science development for attenuation compensation in Cardiac SPECT, The High Country Nuclear Medicine Conference, The Education & Research Foundation of The Society of Nuclear Medicine, Vail, Colorado, February 28 - March 5, 1997. 10. Factors influencing mycardial perfusion quantitation. in “Basic aspects of quantitation of myocardial perfusion”, Categorical Seminar at the Society of Nuclear Medicine’s 44th Annual Meeting, San Antonio, Texas, June 1-5, 1997. 11. Attenuation and Scatter Correction in Myocardial SPECT. Invited lecture at the Annual Spring Meeting of the North Carolina Nuclear Medicine Technologists, Greensboro, NC, March 7-8, 1999. 12. Attenuation Compensation in SPECT: Implementation and Pitfalls, Lecture in the Continuing Education Course: Absolute Quantitation in Cardiac PET, SPECT and Endothelial Dysfunction, at the 46th Annual Meeting of the Society of Nuclear Medicine, Los Angeles, CA, June 6-10, 1999. 13. Siemens Approach to DHCI, Lecture in the Continuing Education Course: Basic Principles and Technical Considerations of Dual Head Gamma Camera Coincidence Imaging (DHGCCI), 46th Annual Meeting of the Society of Nuclear Medicine, June 6-10, 1999. 14. Siemens Approach to Coincidence Imaging, Lecture in the Continuing Education Course: Basic Principles and Technical Considerations of Multi-Head Gamma Coincidence Imaging, 47th Annual Meeting of the Society of Nuclear Medicine, June 3-7, 2000. 15. Image Reconstruction and Attenuation Correction Methods for Cardiac SPECT, Invited presentation at the Society of Nuclear Medicine (SNM) 2003 Mid-Winter Educational Symposium, Hollywood, FL, January 24-26, 2003. 16. Nuclear Medicine Imaging. Invited Presentation in the Refresher Course No. RC417, at the Radiological Society of North America 91st Scientific Assembly and Annual Meeting, McCormick Place, Chicago, Il, November 27 – December 2, 2005
Invited Lectures at Industry Sponsored Meetings 1. Attenuation Correction, GE Users Group Meeting, 40th Annual Society of Nuclear Medicine Meeting, Toronto, Canada, June 8, 1993. 2. Attenuation Compensation in Cardiac SPECT, GE Users Group Meeting, 41th Annual Society of Nuclear Medicine Meeting, Orlando, FL, June 5, 1994. 3. Attenuation Compensation in Cardiac SPECT, GE Users Group Meeting, European Association of Nuclear Medicine Annual Meeting, Dusseldorf, Germany, August 21, 1994. 3. Attenuation and Scatter Compensation Methods in Myocardial SPECT, GE Users Group Meeting, Toronto, Canada, May 4, 1996. 4. Siemens Centers of Excellence Meeting, 1998-2000. 5. Quantitative SPECT, Medium and High Energy SPECT and Ultra High-Resolution Pinhole Small Animal SPECT, Nuclear Medicine Group, Siemens Medical Systems, February 8, 2001. Invited Lectures in Departmental Seminars at Various Universities1. Applications of Monte Carlo Simulations to Medical Physics. Seminar speaker at the University of Massachusetts Medical Center, Worcester, Massachusetts, January 16, 1987. 2. High Resolution SPECT Imaging of the Brain. Seminar speaker at Medical College of Wisconsin, March 5, 1987. 3. SPECT Imaging Research at UNC. Seminar speaker at the Department of Radiology, Henry Ford Hospital, Detroit, Michigan, September 16, 1987. 4. SPECT Imaging of the Brain Using Fan Beam Collimator. Seminar Speaker at the Department of Nuclear Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio, October 26, 1987. 5. Recent Advances SPECT Imaging. Seminar speaker at the Department of Radiology, Memorial Sloan Kettering Hospital, New York, NY, April 4, 1988. 6. Recent Advances in SPECT Imaging. Seminar speaker at the Department of Radiology, University of Utah, Salt Lake City, Utah, April 6, 1988. 7. Recent Advances in SPECT Image Processing and Presentation. Seminar speaker at the Medical Department, Brookhaven National Laboratory, Upton, New York, June 1, 1988. 8. I. The Fundamentals of SPECT Imaging; II. Recent Advances in SPECT Imaging. Guest Lecturer at the Department of Engineering Physics, Tsinghua University, Beijing, The People's Republic of China, October 17-19, 1988. 9. Medical Imaging. Seminar speaker at the Graduate School, Academia Sinica, Beijing, The People's Republic of China, October 19, 1988. 10. I. MR Imaging; II. SPECT Imaging. Guest lecturer at the Wuhan Institute of Physics, Academia Sinica, Wuhan, The People's Republic of China, October 21-22, 1988. 11. SPECT Imaging. Seminar speaker at the Department of Physics, Eastern Carolina University, April 12, 1991 12. Quantitative SPECT Imaging. Invited speaker in the Medical Physics Seminar Series, Department of Nuclear Medicine, the University of Massachusetts Medical Center, Worcester, Massachusetts, March 30, 1992. 13. The Importance and Implementation of Attenuation Compensation in Cardiac SPECT. Invited speaker, Departmental Seminar Series, Department of Nuclear Medicine, the University of Massachusetts Medical Center, Worcester, Massachusetts, February 22, 1993. 14. The Importance and Implementation of Attenuation Compensation in Cardiac SPECT. Invited speaker, Seminar Series, The Joint Program in Nuclear Medicine, Harvard Medical School Department of Radiology, Boston, Massachusetts, February 24, 1993. 15. Recent Advances in SPECT. Invited speaker, Department of Radiology, Tulane University Medical Center, New Orleans, Louisiana, April 26, 1993. 16. Quantitative SPECT Image Reconstruction. Seminar speaker, Department of Radiation Physics, Karolinska Institutet, Stockholm University, Stockholm, Sweden, August 17, 1994. 17. Attenuation Compensation in Cardiac SPECT, Seminar speaker, Department of Nuclear Medicine, Middlesex Hospital, London, United Kingdom, August 25, 1994. 18. An Implementation of Attenuation Compensation Method for Cardiac SPECT. Seminar Speaker, Department of Nuclear Medicine, the University of Massachusetts Medical Center, Worcester, Massachusetts, February 9, 1995. 19. Recent Advances in Instrumentation and Semi-Conductor detector in SPECT. Seminar Speaker, Institute of Nuclear Energy Research, Atomic Energy Council, Lung-tan, Republic of China, August 17, 1995. 20. Attenuation Compensation in SPECT. Seminar Speaker, Tri-Service General Hospital, Taipei, Republic of China, August 17, 1995. 21. Application of Attenuation and Scatter Compensation to Myocardial SPECT. Seminar Speaker, St. Joseph Hospital, Western Ontario University, London, Canada, May 6, 1996. 22. Attenuation and scatter compensation in cardiac SPECT. Seminar Speaker, Memorial Sloane-Kettering Cancer Center, New York, NY, July 1, 1997. 23. Attenuation and scatter compensation in cardiac SPECT. Seminar Speaker, The Brooklyn Hospital, Brooklyn, NY, July 1, 1997. 24. Quantitative functional nuclear imaging: From human to small animals. Seminar Speaker, Department of Biomedical Engineering, Johns Hopkins University, MD, March 19, 2001 25. Oncological SPECT imaging: From human to small animals. Seminar Speaker, Division of Nuclear Medicine, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, September 24, 2001. 26. Oncological SPECT imaging: From human to small animals. Seminar Speaker, Department of Nuclear Medicine, University Medical Center, Utrecht, The Netherlands, November 22, 2001. 27. Quantitative SPECT: From Human to Small Animals, Invited presentation at a Seminar of the Medical Image Processing Group, Department of Radiology, University of Pennsylvania, Philadephia, October 6, 2003. Other Invited Lectures 1. Member, report writing panel. The 5th Nuclear Cardiology Invitational Program of the American Society of Nuclear Cardiology, Bar Harbor, ME, July 15-18, 2000 2. Modeling & Simulation in Medicine: Towards an Integrated Framework, National Library of Medicine, July 20-21, 2000. 3. Functional imaging: From human to small animals. Invited Speaker, North Carolina State University sponsored scientific meeting for North Carolina area Universities, July 2001 ABSTRACTS PRESENTATIONS AT SCIENTIFIC
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